ArticleReproductive sciences (Thousand Oaks, Calif.)2021
Effects of Tannic Acid on Antioxidant Activity and Ovarian Development in Adolescent and Adult Female Brandt's Voles.
Article in Reproductive sciences (Thousand Oaks, Calif.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Effects of Tannic Acid on Immune Function and Gut Microbiota in Brandt's Voles (Microorganisms · 2026Article
- Tannin alleviated reproductive dysfunction in pregnant ewes infected withFrontiers in veterinary science · 2025Article
- Tannic Acid Induces Intestinal Dysfunction and Intestinal Microbial Dysregulation in Brandt's Voles (Animals : an open access journal from MDPI · 2023Article
- Zinc Oxide Particles Can Cause Ovarian Toxicity by Oxidative Stress in Female Mice Model.International journal of nanomedicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well known that tannins can influence the reproduction of animals, but there is little research published to elucidate the mechanics of this phenomenon. The purpose of this study was to investigate the role of antioxidation in the influence of tannic acid on the ovarian development of Brandt's voles (Lasiopodomys brandtii), which is a species of prairie animal that feeds on plants containing tannins. Postnatal 4-week-old female Brandt's voles were treated with 0 (control), 0.3% (low dose), or 0.6% (high dose) tannic acid for 4 or 9 weeks (i.e., when they reached puberty [8 weeks] or sexual maturity [13 weeks], respectively). The results showed that in both adolescent and adult Brandt's voles, firstly, treatment with tannic acid produced a higher ovary coefficient (ratio of the weight of ovaries to body weight), a greater proportion of mature follicles, and an increased follicular diameter. Secondly, tannic acid increased the serum contents of luteinizing hormone, follicle-stimulating hormone, and serum estradiol. Thirdly, tannic acid elevated the levels of antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase) and reduced the level of malondialdehyde. Therefore, it is suggested that tannic acid may promote the ovarian development of female Brant's voles by enhancing their antioxidant capacity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.