Evidence map›Paper›PMID 33844173›Full record

ArticleObesity surgery2021

Changes of Carotid Intima-Media Thickness After Sleeve Gastrectomy in High Cardiovascular Risk Patients: a Prospective Study.

Mohamed Abdalla Salman, Ahmed Abdallah Salman, Mohammad El Sherbiny, Shaimaa Elkholy, Ahmed Youssef, Safa Labib, Mohamed Tag El-Din, Khaled A Monazea, Mohamed Sabry Tourky, Hani Maurice Sabri Mikhail and 9 more

Abstract read
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In one paragraph

Article in Obesity surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Mohamed Abdalla SalmanGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed Abdallah SalmanInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt. awea844@gmail.com.ORCID https://orcid.org/0000-0003-0026-0841
Mohammad El SherbinyInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Shaimaa ElkholyInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed YoussefInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Safa LabibInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Mohamed Tag El-DinGeneral Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Khaled A MonazeaGeneral Surgery Department, Al-Azhar Faculty of Medicine for Boys - Assiut, Al-Azhar University, Assiut, Egypt.
Mohamed Sabry TourkyGreat Western Hospitals NHS Foundation Trust, Swindon, UK.ORCID https://orcid.org/0000-0002-4783-258X
Hani Maurice Sabri MikhailGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Karim K MauriceGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed AbdallahGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Mohamed Saber MostafaGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed Mahmoud HusseinGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed Mohammed AbdelsalamGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Nesrin Abd AllahAnatomy and Embryology Department, Faculty of Medicine, Menoufia University, Shibin Al Kawm, Egypt.
Amr M Ismaeel SaadawyRadiology Department, Faculty of medicine, Ain-Shams University, Cairo, Egypt.
Hossam El-Din ShaabanGastroenterology Department, National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt.
Mohamed D SarhanGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere are insufficient data showing the impact of laparoscopic sleeve gastrectomy (LSG) on carotid intima-media thickness (CIMT). Therefore, in the current work, we investigated the improvement of metabolic syndrome and CIMT in patients with obesity after LSG.

methodsThis study involved 120 consecutively selected Egyptian patients with a high cardiovascular risk who underwent LSG and were followed up for 12 months.

resultsCIMT declined from 0.95 ± 0.17 mm to 0.83 ± 0.12 (p < 0.001) after 12 months. In addition, the mean fasting blood glucose and fasting inulin level dropped significantly from 153.3 ± 63.6 to 108.8 ± 33.8 mg/dl and from 23.1 ± 7.1 mU/ml to 14.1 ± 6.4 respectively (p < 0.001). Furthermore, glycated hemoglobin (HbA1c) declined from 7.02 ± 1.7 to 5.5 ± 0.96 (p < 0.001). At the end of the follow-up period, metabolic parameters such as HOMA-IR, C-reactive protein (CRP), fibrinogen, total cholesterol, LDL cholesterol, triglycerides, AST, and ALT decreased significantly from their respective baselines (p value < 0.001). Moreover, the reduction in CIMT showed a strong positive correlation with the degree of weight loss at 6 months and 12 months of follow-up.

conclusionLSG led to a substantial decrease in CIMT. Moreover, it significantly impacted cardiovascular risk factors such as obesity, hypertension, insulin resistance, lipid profile, and inflammatory markers.

Indexed as

Cardiovascular DiseasesLaparoscopyObesity, MorbidCarotid Intima-Media ThicknessEgyptGastrectomyHeart Disease Risk FactorsHumansProspective StudiesRisk FactorsBariatric surgeryCarotid intima-media thicknessLaparoscopic sleeve gastrectomyMetabolic syndrome

Identifiers

PMID33844173

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.