ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2021
The decrease of non-complicated acute appendicitis and the negative appendectomy rate during pandemic.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04649996 (Variation of Incidence and Clinical Presentation of Acute Appendicitis During a Pandemic.), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Variation of Incidence and Clinical Presentation of Acute Appendicitis During a Pandemic.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Spontaneous Resolution of Uncomplicated Appendicitis may Explain Increase in Proportion of Complicated Appendicitis During Covid-19 Pandemic: a Systematic Review and Meta-analysis.World journal of surgery · 2023Pooled it
- Comparison of the efficacy and safety of antibiotic treatment and appendectomy for acute uncomplicated appendicitis: a systematic review and meta-analysis.BMC surgery · 2023Pooled it
- Nonoperative vs Operative Management of Uncomplicated Acute Appendicitis: A Systematic Review and Meta-analysis.JAMA surgery · 2022Pooled it
- Adaptation of emergency surgical care during successive COVID-19 waves: a single-center analysis of surgically treated acute appendicitis.BMC surgery · 2026Article
- Acute appendicitis before, during, and after the COVID-19 pandemic: a population-based cohort study.Frontiers in surgery · 2026Article
- The rate of complicated appendicitis during a nonpharmaceutical intervention in two territories with different COVID-19 incidence.BMC gastroenterology · 2025Article
- Unusual Incidence of Acute Type A Aortic Dissection during COVID-19.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025Article
- Diagnostic efficacy of ultrasound and computed tomography for acute appendicitis: A single center retrospective study.Medicine · 2025Observational
- Trends in Simple and Complex Appendicitis in Children and the Potential Correlation to Common Viral Pathogens-A Retrospective Cohort Study between 2010 and 2019 in The Netherlands.Children (Basel, Switzerland) · 2023Article
- Impact of the COVID-19 Pandemic on the Severity and Early Postoperative Outcomes of Acute Appendicitis.Cureus · 2023Article
- Acute Appendicitis During The COVID-19 Pandemic: A Multicenter, Retrospective Analysis From The US Epicenter.The American surgeon · 2023Article
- Impact of the COVID-19 pandemic on the outcomes of laparoscopic appendectomy for acute appendicitis.Annals of surgical treatment and research · 2023Article
- Incidence of complicated appendicitis during the COVID-19 pandemic: A systematic review and meta-analysis.International journal of surgery open · 2022Review
- Impact of COVID-19 on the incidence of CT-diagnosed appendicitis and its complications in the UK and Sweden.International journal of colorectal disease · 2022Article
- Omental torsion at the time of COVID-19 in Northern Italy: a case report of conservative management with a review of the pertinent literature.Acta bio-medica : Atenei Parmensis · 2022Review
- Presentation and outcomes of acute appendicitis during COVID-19 pandemic: lessons learned from the Middle East-a multicentre prospective cohort study.International journal of colorectal disease · 2022Article
- Acute appendicitis during the COVID-19 pandemic-changes in incidence and clinical presentation but not in patients' outcome.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2022Article
- A concise pathophysiological model of acute appendicitis against the background of the COVID-19 pandemic.Frontiers in pediatrics · 2022Review
- Answer to letter: The decrease of non-complicated acute appendicitis and the negative appendectomy rate during pandemic.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring pandemic, admissions for surgical emergencies dropped down dramatically. Also acute appendicitis decreased. The aim of the present study was to evaluate the change in volume and clinical presentation of patients with acute appendicitis during pandemic and the variation in treatment.
methodsThis is a retrospective study of patients admitted in 11 Italian hospital for acute appendicitis during the lockdown period (March-April 2020) compared with the same period of the previous 2 years (2018-2019). The number and the rate of complicated and non-complicated acute appendicitis were recorded and compared between the two study periods; non-operative vs operative treatment and negative appendectomy rate were also recorded.
resultsThe study included 532 patients, 112 in the study period and 420 in the control period; Hospital admission for acute appendicitis dropped by 46% (OR 0.516 95% CI 0.411-0.648 p < 0.001) during the 2020 lockdown. The number of complicated acute appendicitis did not change (- 18%, OR 0.763 95% CI 0.517-1.124 p = 0.1719), whereas the number of non-complicated acute appendicitis significantly decreased (- 56%, OR 0.424 95% CI 0.319-0.564 p < 0.001). Non-operative treatment rate remained similar (12.1% vs. 11.6% p = 0.434). The negative appendectomy rate also significantly decreased (6.1% vs. 17.3%, p = 0.006).
conclusionsThe present study found a significant reduction of both admissions for non-complicated acute appendicitis and negative appendectomy rate during the pandemic period. Conversely, admissions for complicated acute appendicitis did not change.
trial registrationNCT04649996.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.