Evidence map›Paper›PMID 33843700›Full record

ArticleJournal of neonatal-perinatal medicine2021

Micro-premature infants in New Jersey show improved mortality and morbidity from 2000-2018.

M Cohen, H Perl, E Steffen, B Planer, A Kushnir, S Hudome, D Brown, M Myers, New Jersey NICU Collaborative

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Article in Journal of neonatal-perinatal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

M CohenDepartment of Pediatrics, Children's Hospital of New Jersey, Newark, NJ, USA.
H PerlJoseph M. Sanzari Children's Hospital, HUMC, Hackensack, NJ, USA.
E SteffenDepartment of Pediatrics, Saint Barnabas Medical Center, Livingston, NJ, USA.
B PlanerJoseph M. Sanzari Children's Hospital, HUMC, Hackensack, NJ, USA.
A KushnirDepartment of Pediatrics, Cooper Children's Regional Hospital, Camden, NJ, USA.
S HudomeUnterberg Children's Hospital at Monmouth M.C., Long Branch, NJ, USA.
D BrownDepartment of Pediatrics, Children's Hospital of New Jersey, Newark, NJ, USA.
M MyersDepartment of Pediatrics, Children's Hospital of New Jersey, Newark, NJ, USA.
New Jersey NICU Collaborative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicro-premature newborns, gestational age (GA) ≤ 25 weeks, have high rates of mortality and morbidity. Literature has shown improving outcomes for extremely low gestational age newborns (ELGANs) GA ≤ 29 weeks, but few studies have addressed outcomes of ELGANs ≤ 25 weeks.

objectiveTo evaluate the trends in outcomes for ELGANs born in New Jersey, from 2000 to 2018 and to compare two subgroups: GA 23 to 25 weeks (E1) and GA 26 to 29 weeks (E2).

methodsThirteen NICUs in NJ submitted de-identified data. Outcomes for mortality and morbidity were calculated.

resultsData from 12,707 infants represents the majority of ELGANs born in NJ from 2000 to 2018. There were 3,957 in the E1 group and 8,750 in the E2 group. Mortality decreased significantly in both groups; E1, 43.2% to 30.2% and E2, 7.6% to 4.5% over the 19 years. The decline in E1 was significantly greater than in E2. Most morbidities also showed significant improvement over time in both groups. Survival without morbidity increased from 14.5% to 30.7% in E1s and 47.2% to 69.9% in E2s. Similar findings held for 501-750 and 751-1000g birth weight strata.

conclusionsSignificant declines in both mortality and morbidity have occurred in ELGANs over the last two decades. These rates of improvements for the more immature ELGANs of GA 230 to 256 weeks were greater than for the more mature group in several outcomes. While the rates of morbidity and mortality remain high, these results validate current efforts to support the micro-premature newborn.

Indexed as

Infant, Premature, DiseasesGestational AgeHumansInfantInfant, Low Birth WeightInfant, NewbornInfant, PrematureMorbidityNew JerseyELGANKeywords: Collaborativemicro-prematuremorbiditymortalityneonatologyNew Jerseyoutcomestrends

Identifiers

PMID33843700
PMCPMC8673536

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.