Evidence map›Paper›PMID 33843602›Full record

ArticleJournal of medical Internet research2021

Effects of an Animated Blood Clot Technology (Visual Clot) on the Decision-Making of Users Inexperienced in Viscoelastic Testing: Multicenter Trial.

Sadiq Said, Tadzio Raoul Roche, Julia Braun, Micheal Thomas Ganter, Patrick Meybohm, Johannes Herrmann, Kai Zacharowski, Florian Jürgen Raimann, Florian Piekarski, Eva Rivas and 4 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of medical Internet research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Sadiq SaidInstitute of Anesthesiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-2037-4766
Tadzio Raoul RocheInstitute of Anesthesiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-1072-5748
Julia BraunDepartment of Epidemiology, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-8359-6177
Micheal Thomas GanterInstitute of Anesthesiology and Pain Therapy, Cantonal Hospital Winterthur, Winterthur, Switzerland.ORCID 0000-0003-1234-1833
Patrick MeybohmDepartment of Anesthesiology, Intensive Care, Emergency, and Pain Medicine, University Hospital Wuerzburg, University of Wuerzburg, Wuerzburg, Germany.ORCID 0000-0002-2666-8696
Johannes HerrmannDepartment of Anesthesiology, Intensive Care, Emergency, and Pain Medicine, University Hospital Wuerzburg, University of Wuerzburg, Wuerzburg, Germany.ORCID 0000-0002-2169-3761
Kai ZacharowskiDepartment of Anesthesiology, Intensive Care Medicine, and Pain Therapy, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany.ORCID 0000-0002-0212-9110
Florian Jürgen RaimannDepartment of Anesthesiology, Intensive Care Medicine, and Pain Therapy, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany.ORCID 0000-0002-6597-9585
Florian PiekarskiDepartment of Anesthesiology, Intensive Care Medicine, and Pain Therapy, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany.ORCID 0000-0002-4095-3573
Eva RivasDepartment of Anesthesiology, Intensive Care Medicine, and Pain Therapy, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.ORCID 0000-0002-5816-998X
Manuel López-BaamondeDepartment of Anesthesiology, Intensive Care Medicine, and Pain Therapy, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.ORCID 0000-0001-5537-1755
Donat R SpahnInstitute of Anesthesiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-4782-183X
Christoph Beat NöthigerInstitute of Anesthesiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-0336-1421
David Werner TschollInstitute of Anesthesiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-3677-3705
University of Zurich · CHGoethe University Frankfurt · DEUniversitat de Barcelona · ESUniversitätsklinikum Würzburg · DEKantonsspital Winterthur · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundViscoelastic test-guided coagulation management has become increasingly important in assessing hemostasis. We developed Visual Clot, an animated, 3D blood clot that illustrates raw rotational thromboelastometry (ROTEM) parameters in a user-centered and situation awareness-oriented method.

objectiveThis study aimed to evaluate the applicability of Visual Clot by examining its effects on users that are novices in viscoelastic-guided resuscitation.

methodsWe conducted an investigator-initiated, international, multicenter study between September 16, 2020, and October 6, 2020, in 5 tertiary care hospitals in central Europe. We randomly recruited medical students and inexperienced resident physicians without significant prior exposure to viscoelastic testing. The 7 participants per center managed 9 different ROTEM outputs twice, once as standard ROTEM tracings and once as the corresponding Visual Clot. We randomly presented the 18 viscoelastic cases and asked the participants for their therapeutic decisions. We assessed the performance, diagnostic confidence, and perceived workload in managing the tasks using mixed statistical models and adjusted for possible confounding factors.

resultsAnalyzing a total of 630 results, we found that the participants solved more cases correctly (odds ratio [OR] 33.66, 95% CI 21.13-53.64; P<.001), exhibited more diagnostic confidence (OR 206.2, 95% CI 93.5-454.75; P<.001), and perceived less workload (coefficient -41.63; 95% CI -43.91 to -39.36; P<.001) using Visual Clot compared to using standard ROTEM tracings.

conclusionsThis study emphasizes the practical benefit of presenting viscoelastic test results in a user-centered way. Visual Clot may allow inexperienced users to be involved in the decision-making process to treat bleeding-associated coagulopathy. The increased diagnostic confidence, diagnostic certainty, reduced workload, and positive user feedback associated with this visualization may promote the further adoption of viscoelastic methods in diverse health care settings.

Indexed as

Blood Coagulation DisordersThrombosisHemostasisHumansTechnologyThrombelastographyavatar technologycoagulation managementhemostasisintuitive designrotational thromboelastometrytestinguser-centered designVisual Clot

Identifiers

PMID33843602
PMCPMC8129883
OpenAlexW3152794166

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.