Evidence map›Paper›PMID 33843585›Full record

ArticleeLife2021

Gamma rhythms and visual information in mouse V1 specifically modulated by somatostatin

Mahmood S Hoseini, Bryan Higashikubo, Frances S Cho, Andrew H Chang, Alexandra Clemente-Perez, Irene Lew, Agnieszka Ciesielska, Michael P Stryker, Jeanne T Paz

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mahmood S Hoseini *University of California, San Francisco, Department of Physiology, San Francisco, United States.ORCID 0000-0002-3139-0561
Bryan Higashikubo *Gladstone Institute of Neurological Disease, San Francisco, United States.
Frances S ChoGladstone Institute of Neurological Disease, San Francisco, United States.ORCID 0000-0002-2576-7801
Andrew H ChangGladstone Institute of Neurological Disease, San Francisco, United States.
Alexandra Clemente-PerezGladstone Institute of Neurological Disease, San Francisco, United States.
Irene LewGladstone Institute of Neurological Disease, San Francisco, United States.ORCID 0000-0003-0153-1236
Agnieszka CiesielskaGladstone Institute of Neurological Disease, San Francisco, United States.
Michael P Stryker *University of California, San Francisco, Department of Physiology, San Francisco, United States.ORCID 0000-0003-1546-5831
Jeanne T Paz *Gladstone Institute of Neurological Disease, San Francisco, United States.ORCID 0000-0001-6339-8130
Gladstone Institutes · USUniversity of California, San Francisco · US

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAKKARAJU, APARNA · 1985 to 2024
$16.8M
DEVELOPMENT &PLASTICITY OF THE VISUAL SYSTEMR01EY002874 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STRYKER, MICHAEL P · 1986 to 2022
$6.4M
The Role of Inflammation in Post-stroke EpileptogenesisR01NS096369 · NINDS · J. DAVID GLADSTONE INSTITUTES · PI PAZ, JEANNE T · 2016 to 2021
$2.3M
EXTRAMULAR RESEARCH FACILITIES CONSTRUCTIONC06RR018928 · NCRR · J. DAVID GLADSTONE INSTITUTES · PI MAHLEY, ROBERT W. · 2003 to 2003
$2.1M
Interneuron Precursors and the induction of cortical plasticityR01EY025174 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALVAREZ-BUYLLA, ARTURO, HASENSTAUB, ANDREA RAYNE · 2015 to 2019
$2.1M
Functional Connectivity of Primary Visual CortexR01EY013595 · NEI · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI STRYKER, MICHAEL PAUL · 2001 to 2004
$1.5M
Determining the role of dysregulated GABA uptake by reactive astrocytes in thalamic circuit hyperexcitability and seizuresF31NS111819 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHO, FRANCES · 2019 to 2020
$75k
NCRR NIH HHS C06 RR018928NEI NIH HHS P30 EY002162NEI NIH HHS R01 EY002874NEI NIH HHS R01 EY013595NEI NIH HHS R01 EY025174NINDS NIH HHS F31 NS111819NINDS NIH HHS R01 NS096369NINDS NIH HHS R01NS096369
6 · The paper itself

Abstract

Visual perception in natural environments depends on the ability to focus on salient stimuli while ignoring distractions. This kind of selective visual attention is associated with gamma activity in the visual cortex. While the nucleus reticularis thalami (nRT) has been implicated in selective attention, its role in modulating gamma activity in the visual cortex remains unknown. Here, we show that somatostatin- (SST) but not parvalbumin-expressing (PV) neurons in the visual sector of the nRT preferentially project to the dorsal lateral geniculate nucleus (dLGN), and modulate visual information transmission and gamma activity in primary visual cortex (V1). These findings pinpoint the SST neurons in nRT as powerful modulators of the visual information encoding accuracy in V1 and represent a novel circuit through which the nRT can influence representation of visual information.

Indexed as

AnimalsFemaleGamma RhythmMaleMiceNeuronsSomatostatinThalamic NucleiVisual CortexVisual PerceptionSomatostatingamma oscillationsinformation transmissionmouseneurosciencenucleus reticularis thalamioptogeneticsthalamocortical visual circuitsvisual cortex

Identifiers

PMID33843585
PMCPMC8064751
OpenAlexW3155100327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.