Evidence map›Paper›PMID 33843555›Full record

ArticleCNS spectrums2021

The place of obsessive-compulsive and related disorders in the compulsive-impulsive spectrum: a cluster-analytic study.

Leonardo F Fontenelle, Louise Destrée, Mary-Ellen Brierley, Emma M Thompson, Murat Yücel, Rico Lee, Lucy Albertella, Sam R Chamberlain

Abstract read
In one paragraph

Article in CNS spectrums, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leonardo F FontenelleTurner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.ORCID https://orcid.org/0000-0001-9075-8226
Louise DestréeTurner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.
Mary-Ellen BrierleyTurner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.
Emma M ThompsonTurner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.
Murat YücelTurner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.
Rico LeeTurner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.
Lucy AlbertellaTurner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.ORCID https://orcid.org/0000-0001-5232-6414
Sam R ChamberlainDepartment of Psychiatry, University of Southampton; and Department of Psychiatry, University of Cambridge, UK.ORCID https://orcid.org/0000-0001-7014-8121

Funding

Wellcome Trust 110049
6 · The paper itself

Abstract

backgroundThe extent to which obsessive-compulsive and related disorders (OCRDs) are impulsive, compulsive, or both requires further investigation. We investigated the existence of different clusters in an online nonclinical sample and in which groups DSM-5 OCRDs and other related psychopathological symptoms are best placed.

methodsSeven hundred and seventy-four adult participants completed online questionnaires including the Cambridge-Chicago Compulsivity Trait Scale (CHI-T), the Barratt Impulsiveness Scale (BIS-15), and a series of DSM-5 OCRDs symptom severity and other psychopathological measures. We used K-means cluster analysis using CHI-T and BIS responses to test three and four factor solutions. Next, we investigated whether different OCRDs symptoms predicted cluster membership using a multinomial regression model.

resultsThe best solution identified one "healthy" and three "clinical" clusters (ie, one predominantly "compulsive" group, one predominantly "impulsive" group, and one "mixed"-"compulsive and impulsive group"). A multinomial regression model found obsessive-compulsive, body dysmorphic, and schizotypal symptoms to be associated with the "mixed" and the "compulsive" clusters, and hoarding and emotional symptoms to be related, on a trend level, to the "impulsive" cluster. Additional analysis showed cognitive-perceptual schizotypal symptoms to be associated with the "mixed" but not the "compulsive" group.

conclusionsOur findings suggest that obsessive-compulsive disorder; body dysmorphic disorder and schizotypal symptoms can be mapped across the "compulsive" and "mixed" clusters of the compulsive-impulsive spectrum. Although there was a trend toward hoarding being associated with the "impulsive" group, trichotillomania, and skin picking disorder symptoms did not clearly fit to the demarcated clusters.

Indexed as

body dysmorphic disorderCompulsivityhoarding disorderimpulsivityobsessive–compulsive disordertrichotillomania

Identifiers

PMID33843555
PMCPMC7616490

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.