Evidence map›Paper›PMID 33843452›Full record

ArticlemAbs

Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid protein.

Curtis D Hodge, Daniel J Rosenberg, Patricia Grob, Mateusz Wilamowski, Andrzej Joachimiak, Greg L Hura, Michal Hammel

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in mAbs. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Effects ofFrontiers in molecular biosciences · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Curtis D HodgeMolecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Daniel J RosenbergMolecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Patricia GrobHoward Hughes Medical Institute, UC Berkeley, Berkeley, CA, USA.
Mateusz WilamowskiCenter for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, USA.
Andrzej JoachimiakCenter for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, USA.
Greg L HuraMolecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Michal HammelMolecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Lawrence Berkeley National Laboratory · USJoint Center for Structural Genomics · USQB3 · USUniversity of California, Berkeley · US

Funding

Transcription-Coupled & Replication-Associated Excision RepairP01CA092584 · NCI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI WALTER J. CHAZIN · 2001 to 2026
$89.6M
User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6M
NCI NIH HHS P01 CA092584NIAID NIH HHS HHSN272201700060CNIGMS NIH HHS P30 GM124169NIGMS NIH HHS P30 GM124169-01
6 · The paper itself

Abstract

Monoclonal antibodies (mAbs) are the basis of treatments and diagnostics for pathogens and other biological phenomena. We conducted a structural characterization of mAbs against the N-terminal domain of nucleocapsid protein (NP

Indexed as

AnimalsAntibodies, MonoclonalAntibodies, ViralCOVID-19EpitopesHumansNucleocapsid ProteinsSARS-CoV-2Antibodies, MonoclonalAntibodies, ViralEpitopesNucleocapsid ProteinsflexibilitymAbs polymerizationnucleocapsidSARS-cov-2small-angle x-ray scattering

Identifiers

PMID33843452
PMCPMC8043170
OpenAlexW3154045689

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.