Evidence map›Paper›PMID 33843016›Full record

SynthesisWorld journal of urology2021

Robot-assisted radical prostatectomy versus standard laparoscopic radical prostatectomy: an evidence-based analysis of comparative outcomes.

Umberto Carbonara, Maya Srinath, Fabio Crocerossa, Matteo Ferro, Francesco Cantiello, Giuseppe Lucarelli, Francesco Porpiglia, Michele Battaglia, Pasquale Ditonno, Riccardo Autorino

Abstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 5 pooled it
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 5 syntheses or guidelines pooled it, 80 citations in OpenAlex.

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  10. [First cohort: Robotic radical prostatectomy at the Mexican Institute for Social Security].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Umberto Carbonara *Division of Urology, VCU Health, Richmond, VA, 23298-0118, USA.
Maya Srinath *Division of Urology, VCU Health, Richmond, VA, 23298-0118, USA.
Fabio CrocerossaDivision of Urology, VCU Health, Richmond, VA, 23298-0118, USA.
Matteo FerroDepartment of Urology, European Institute of Oncology, IRCCS, Milan, Italy.
Francesco CantielloDepartment of Urology, Magna Graecia University, Catanzaro, Italy.
Giuseppe LucarelliDepartment of Emergency and Organ Transplantation-Urology, Andrology and Kidney Transplantation Unit, University of Bari, Bari, Italy.
Francesco PorpigliaDepartment of Urology, San Luigi Hospital, University of Turin, Orbassano, Italy.
Michele BattagliaDepartment of Emergency and Organ Transplantation-Urology, Andrology and Kidney Transplantation Unit, University of Bari, Bari, Italy.
Pasquale DitonnoDepartment of Emergency and Organ Transplantation-Urology, Andrology and Kidney Transplantation Unit, University of Bari, Bari, Italy.
Riccardo AutorinoDivision of Urology, VCU Health, Richmond, VA, 23298-0118, USA. ricautor@gmail.com.ORCID http://orcid.org/0000-0001-7045-7725
Children's Hospital of Richmond at VCU · USMagna Graecia University · ITUniversity of Bari Aldo Moro · ITEuropean Institute of Oncology · ITIstituto Tumori Bari · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo provide a systematic analysis of the comparative outcomes of robot-assisted radical prostatectomy (RARP) versus laparoscopic radical prostatectomy (LRP) in the treatment of prostate cancer based on the best currently available evidence.

methodsAn independent systematic review of the literature was performed up to February 2021, using MEDLINE

resultsTwenty-six studies were identified. Only 16 "high-quality" (RCTs and Newcastle-Ottawa scale 8-9) studies were included in the meta-analysis. Among the 13,752 patients included, 6135 (44.6%) and 7617 (55.4%) were RARP and LRP, respectively. There was no difference between groups in terms of demographics and clinical characteristics. Overall and major complication (Clavien-Dindo ≥ III) rates were similar in LRP than RARP group. The biochemical recurrence (BCR) rate at 12months was significantly lower for RARP (OR: 0.52; 95% CI 0.43-0.63; p < 0.00001). RARP reported lower urinary incontinence rate at 12months (OR: 0.38; 95% CI 0.18-0.8; p = 0.01). The erectile function recovery rate at 12months was higher for RARP (OR: 2.16; 95% CI 1.23-3.78; p = 0.007).

conclusionCurrent evidence shows that RARP offers favorable outcomes compared with LRP, including higher potency and continence rates, and less likelihood of BCR. An assessment of longer-term outcomes is lacking, and higher cost remains a concern of robotic versus laparoscopic prostate cancer surgery.

Indexed as

Erectile DysfunctionEvidence-Based PracticeHumansLaparoscopyMaleNeoplasm Recurrence, LocalPostoperative ComplicationsProstatectomyProstate-Specific AntigenProstatic NeoplasmsRecovery of FunctionRobotic Surgical ProceduresUrinary IncontinenceProstate-Specific AntigenLaparoscopic radical prostatectomyMeta-analysisProstatic cancerRobotic radical prostatectomy

Identifiers

PMID33843016
OpenAlexW3156751090

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.