Evidence map›Paper›PMID 33842926›Full record

ReviewBiophysics reviews2021

Addressing cervical cancer screening disparities through advances in artificial intelligence and nanotechnologies for cellular profiling.

Zhenzhong Yang, Jack Francisco, Alexandra S Reese, David R Spriggs, Hyungsoon Im, Cesar M Castro

Abstract readReview
In one paragraph

Review in Biophysics reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandra S ReeseCancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.ORCID https://orcid.org/0000-0003-2867-8924
David R SpriggsCancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.ORCID https://orcid.org/0000-0003-2174-4992

Funding

Development of plasmon-enhanced biosensing for multiplexed profiling of extracellular vesiclesR01GM138778 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI IM, HYUNGSOON · 2020 to 2024
$2.3M
Novel Nano-Plasmonic Technology for Quantitative Analysis of Cancer ExosomesR00CA201248 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI IM, HYUNGSOON · 2017 to 2019
$968k
Nano-plasmonic technology for high-throughput single exosome analysesR21CA217662 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI IM, HYUNGSOON · 2019 to 2021
$585k
NCI NIH HHS R00 CA201248NCI NIH HHS R21 CA217662NIGMS NIH HHS R01 GM138778
6 · The paper itself

Abstract

Almost all cases of cervical cancer are caused by the human papilloma virus (HPV). Detection of pre-cancerous cervical changes provides a window of opportunity for cure of an otherwise lethal disease when metastatic. With a greater understanding of the biology and natural course of high-risk HPV infections, screening methods have shifted beyond subjective Pap smears toward more sophisticated and objective tactics. This has led to a substantial growth in the breadth and depth of HPV-based cervical cancer screening tests, especially in developed countries without constrained resources. Many low- and middle-income countries (LMICs) have less access to advanced laboratories and healthcare resources, so new point-of-care (POC) technologies have been developed to provide test results in real time, improve the efficiency of techniques, and increase screening adoption. In this Review, we will discuss how novel decentralized screening technologies and computational strategies improve upon traditional methods and how their realized promise could further democratize cervical cancer screening and promote greater disease prevention.

Identifiers

PMID33842926
PMCPMC8015256

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.