Evidence map›Paper›PMID 33842925›Full record

ArticleJournal of the American College of Emergency Physicians open2021

Quantitative pleural line characterization outperforms traditional lung texture ultrasound features in detection of COVID-19.

Laith R Sultan, Yale Tung Chen, Theodore W Cary, Khalid Ashi, Chandra M Sehgal

Open access · goldAbstract read
In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  4. New International Guidelines and Consensus on the Use of Lung Ultrasound.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Laith R SultanDepartment of Radiology University of Pennsylvania Philadelphia Pennsylvania USA.
Yale Tung ChenDepartment of Emergency Medicine Hospital Universitario La Paz Madrid Spain.
Theodore W CaryDepartment of Radiology University of Pennsylvania Philadelphia Pennsylvania USA.
Khalid AshiDepartment of Radiology University of Pennsylvania Philadelphia Pennsylvania USA.
Chandra M SehgalDepartment of Radiology University of Pennsylvania Philadelphia Pennsylvania USA.
University of Pennsylvania · USHospital Universitario La Paz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveLung ultrasound is an inherently user-dependent modality that could benefit from quantitative image analysis. In this pilot study we evaluate the use of computer-based pleural line (p-line) ultrasound features in comparison to traditional lung texture (TLT) features to test the hypothesis that p-line thickening and irregularity are highly suggestive of coronavirus disease 2019 (COVID-19) and can be used to improve the disease diagnosis on lung ultrasound.

methodsTwenty lung ultrasound images, including normal and COVID-19 cases, were used for quantitative analysis. P-lines were detected by a semiautomated segmentation method. Seven quantitative features describing thickness, margin morphology, and echo intensity were extracted. TLT lines were outlined, and texture features based on run-length and gray-level co-occurrence matrix were extracted. The diagnostic performance of the 2 feature sets was measured and compared using receiver operating characteristics curve analysis. Observer agreements were evaluated by measuring interclass correlation coefficients (ICC) for each feature.

resultsSix of 7 p-line features showed a significant difference between normal and COVID-19 cases. Thickness of p-lines was larger in COVID-19 cases (6.27 ± 1.45 mm) compared to normal (1.00 ± 0.19 mm),

conclusionP-line features characterize COVID-19 changes with high accuracy and outperform TLT features. Quantitative p-line features are promising diagnostic tools in the interpretation of lung ultrasound images in the context of COVID-19.

Indexed as

coronavirusCOVID‐19lung ultrasoundpleural linepoint‐of‐care ultrasound (POCUS)quantitative features

Identifiers

PMID33842925
PMCPMC8018308
OpenAlexW3147797929

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.