Evidence map›Paper›PMID 33842885›Full record

ArticleBrain communications2021

Detection of β-amyloid positivity in Alzheimer's Disease Neuroimaging Initiative participants with demographics, cognition, MRI and plasma biomarkers.

Duygu Tosun, Dallas Veitch, Paul Aisen, Clifford R Jack, William J Jagust, Ronald C Petersen, Andrew J Saykin, James Bollinger, Vitaliy Ovod, Kwasi G Mawuenyega and 6 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 3 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Observational
  5. Article
  6. Tracking early cognitive decline in preclinical AD with brain MRI similarity.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Deep Learning-Based Prediction of PET Amyloid Status Using MRI.AJNR. American journal of neuroradiology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Beyond Macrostructure: Is There a Role for Radiomics Analysis in Neuroimaging ?Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 3 countries.

Duygu TosunSan Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Dallas VeitchDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Paul AisenAlzheimer's Therapeutic Research Institute (ATRI), Keck School of Medicine, University of Southern California, San Diego, CA, USA.
Clifford R JackDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0000-0001-7916-622X
William J JagustSchool of Public Health and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.ORCID https://orcid.org/0000-0002-4458-113X
Ronald C PetersenDivision of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Andrew J SaykinDepartment of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA.
James BollingerDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Vitaliy OvodDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Kwasi G MawuenyegaDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Randall J BatemanDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Leslie M ShawDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
John Q TrojanowskiDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kaj BlennowDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0003-3930-4354
Michael W WeinerSan Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Washington University in St. Louis · USMayo Clinic in Arizona · USSahlgrenska University Hospital · SESan Francisco VA Medical Center · USUniversity of Pennsylvania · USIndiana University School of MedicineUniversity of California, Berkeley · USUniversity of California, San Francisco · USUniversity of Southern California · US

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Blood amyloid-beta relationship with amyloid plaques and CSF amyloid-betaRF1AG061900 · NIA · WASHINGTON UNIVERSITY · PI BATEMAN, RANDALL J · 2019 to 2020
$6.9M
Blood amyloid-beta relationship with amyloid plaques and CSF amyloid-betaR56AG061900 · NIA · WASHINGTON UNIVERSITY · PI BATEMAN, RANDALL J · 2018 to 2018
$1.4M
NIA NIH HHS R56 AG061900NIA NIH HHS RF1 AG061900NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’sMRIPETplasmaβ-amyloid

Identifiers

PMID33842885
PMCPMC8023542
OpenAlexW3127106548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.