ArticleEClinicalMedicine2021
An evaluation of the mental health impact of SARS-CoV-2 on patients, general public and healthcare professionals: A systematic review and meta-analysis.
Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 15 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
71 citing papers in PubMed, 15 syntheses or guidelines pooled it, 125 citations in OpenAlex.
- Temporal patterns of suicidal ideation prevalence during the COVID-19 pandemic: a systematic review and meta-analysis of cross-sectional and longitudinal studies.Epidemiology and psychiatric sciences · 2025Pooled it
- Pooled it
- An umbrella review of the prevalence of depression during the COVID-19 pandemic: Call to action for post-COVID-19 at the global level.BMC public health · 2024Pooled it
- Online Group Psychotherapy: A Systematic Review.Community mental health journal · 2024Pooled it
- Estimation of the prevalence of anxiety during the COVID-19 pandemic: A meta-analysis of meta-analyses.BMC public health · 2024Pooled it
- Mindfulness-based interventions for improving mental health of frontline healthcare professionals during the COVID-19 pandemic: a systematic review.Systematic reviews · 2024Pooled it
- Pooled it
- The prevalence of probable mental health disorders among hospital healthcare workers during COVID-19: A systematic review and meta-analysis.Journal of affective disorders · 2023Pooled it
- COVID-19 and common mental health symptoms in the early phase of the pandemic: An umbrella review of the evidence.PLoS medicine · 2023Pooled it
- Mental Health Impact of Early Stages of the COVID-19 Pandemic on Individuals with Pre-Existing Mental Disorders: A Systematic Review of Longitudinal Research.International journal of environmental research and public health · 2023Pooled it
- Have Deaths of Despair Risen during the COVID-19 Pandemic? A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action.Molecular psychiatry · 2022Pooled it
- Impact of the COVID-19 pandemic on the mental health of hospital staff: An umbrella review of 44 meta-analyses.International journal of nursing studies · 2022Pooled it
- Suicidal ideation and suicide attempts in healthcare professionals during the COVID-19 pandemic: A systematic review.Frontiers in public health · 2022Pooled it
- COVID-19 Pandemic and Overall Mental Health of Healthcare Professionals Globally: A Meta-Review of Systematic Reviews.Frontiers in psychiatry · 2021Pooled it
- Harmonising Depression and Anxiety Measures Across International Cohorts: A Framework Validated Using Measurement Invariance.International journal of methods in psychiatric research · 2026Article
- Faculty of Radiation Oncology 2022 New Zealand Workforce Census.Journal of medical imaging and radiation oncology · 2026Article
- Experiences of Loss and Grief Among Brazilian Frontline Healthcare Professionals During the COVID-19 Pandemic Crisis: A Grounded Theory Analysis.Healthcare (Basel, Switzerland) · 2026Article
- Association between isolation room admission in intensive care units and long-term psychiatric disorders: a nationwide cohort study.Critical care (London, England) · 2025Article
- Analyzing Health Care Professionals' Resilience and Emotional Responses to COVID-19 via Twitter: Retrospective Cohort and Matched Comparison Group Study.Journal of medical Internet research · 2025Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe global impact of COVID-19 pandemic continues to affect the lives of billions of people with recurrent waves. Healthcare systems are struggling to manage pre-existing patient care and recurring covid-19 demands. As a result, we evaluated the mental health impact using systematic review and meta-analysis.
methodsA comprehensive search was undertaken from April 2020 to 22nd January 2021 using multiple electronic databases. A systematic review protocol was developed and published on PROSPERO registration; CRD42020181481. A random-effects model was used to compute pooled estimates of anxiety, depression, PTSD, insomnia and suicidal thoughts.
findingsOur search yielded 11,295 studies and of those 287 met the inclusion criteria. The meta-analysis of 206 studies revealed minimal differences in prevalence of anxiety, depression, and PTSD among HCPs compared with the public during the pandemic but higher prevalence of suicidal thoughts/ideation or self-harm (11% vs 5.8%) and lower prevalence of wellbeing (28.2% vs 52.6%) among the public compared to HCPs.
interpretationThe pandemic has led to a high mental health burden especially amongst HCPs and higher suicidal ideation and lower wellbeing in general public which warrants further investigation and management globally. These findings highlight an emerging critical public health issue that requires urgent solutions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.