Evidence map›Paper›PMID 33842847›Full record

ArticleFASEB bioAdvances2021

Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach of genomic DNA.

Claire R Quilter, Kerry M Harvey, Julien Bauer, Benjamin M Skinner, Maria Gomez, Manu Shrivastava, Andrew M Doel, Saikou Drammeh, David B Dunger, Sophie E Moore and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB bioAdvances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Claire R QuilterDepartment of Pathology University of Cambridge Cambridge UK.
Kerry M HarveyDepartment of Pathology University of Cambridge Cambridge UK.
Julien BauerDepartment of Pathology University of Cambridge Cambridge UK.
Benjamin M SkinnerDepartment of Pathology University of Cambridge Cambridge UK.
Maria GomezDepartment of Pathology University of Cambridge Cambridge UK.
Manu ShrivastavaDepartment of Pathology University of Cambridge Cambridge UK.
Andrew M DoelDepartment of Women and Children's Health King's College London London UK.
Saikou DrammehMRC Unit The Gambia at London School of Hygiene and Tropical Medicine Banjul The Gambia.
David B DungerMRC Epidemiology Unit University of Cambridge School of Clinical Medicine Cambridge UK.
Sophie E MooreDepartment of Women and Children's Health King's College London London UK.
Ken K OngMRC Epidemiology Unit University of Cambridge School of Clinical Medicine Cambridge UK.
Andrew M PrenticeMRC Unit The Gambia at London School of Hygiene and Tropical Medicine Banjul The Gambia.
Robin M BernsteinGrowth and Development Lab Department of Anthropology University of Colorado Boulder CO USA.ORCID https://orcid.org/0000-0001-8805-7527
Carole A SargentDepartment of Pathology University of Cambridge Cambridge UK.
Nabeel A AffaraDepartment of Pathology University of Cambridge Cambridge UK.
University of Cambridge · GBKing's College London · GBMRC Unit the Gambia · GMUniversity of Colorado Boulder · USUniversity of Essex · GB

Funding

Medical Research Council MC_EX_MR/M01424X/1Medical Research Council MC_PC_MR/R020183/1Medical Research Council MC_U123292700Medical Research Council MC_U123292701Medical Research Council MC_UP_1005/1Medical Research Council MC_UU_00006/2Medical Research Council MC_UU_00026/3Medical Research Council MC_UU_12015/2Medical Research Council MR/P012019/1Medical Research Council MR/T032863/1
6 · The paper itself

Abstract

Low birthweight and reduced height gain during infancy (stunting) may arise at least in part from adverse early life environments that trigger epigenetic reprogramming that may favor survival. We examined differential DNA methylation patterns using targeted methyl sequencing of regions regulating gene activity in groups of rural Gambian infants: (a) low and high birthweight (DNA from cord blood (

Indexed as

birthweightDNA methylationenvironmental exposuresstunting

Identifiers

PMID33842847
PMCPMC8019263
OpenAlexW3124190900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.