ArticleAmerican journal of ophthalmology case reports2021
Orbital infarction syndrome following hyaluronic acid filler rhinoplasty.
Article in American journal of ophthalmology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Advances of Hyaluronic Acid Nasal Injection Techniques and Complications: A Systematic Review.Aesthetic plastic surgery · 2025Pooled it
- Administration Method and Potential Efficacy of Hyaluronidase for Hyaluronic Acid Filler-Related Vision Loss: A Systematic Review.Aesthetic plastic surgery · 2024Pooled it
- Ocular Complications Post-Cosmetic Periocular Hyaluronic Acid Injections: A Systematic Review.Aesthetic plastic surgery · 2022Pooled it
- Adverse reactions and complications caused by hyaluronic acid injections in the face: A scoping review.Brazilian dental journal · 2026Article
- Cerebral Venous Thrombosis Following Periocular Filler Injection-A Case Report and Review of Literature.Case reports in neurological medicine · 2025Article
- "Filler-Associated Acute Stroke Syndrome": Classification, Predictive Modelling of Hyaluronidase Efficacy, and Updated Case Review on Neurological and Visual Complications.Aesthetic plastic surgery · 2024Review
- Penetrating globe injury during rhinoplasty surgery; A case report.JPRAS open · 2023Article
- Bridging a Century-Old Problem: The Pathophysiology and Molecular Mechanisms of HA Filler-Induced Vascular Occlusion (FIVO)-Implications for Therapeutic Interventions.Molecules (Basel, Switzerland) · 2022Review
- Orbital Infarction Syndrome Following Hyaluronic Acid Lip Filler Injection.Ophthalmic plastic and reconstructive surgeryArticle
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOver the last decade, injectable soft tissue fillers have become an essential part of facial plastic surgery practice. We report here a tragic complication of hyaluronic acid filler injection in a young healthy woman, management offered, and the outcome. OBSERVATIONS: A 32-year-old woman developed unilateral acute blindness, orbital pain, total ophthalmoplegia, and anterior and posterior segment ischemia immediately following hyaluronic acid injection. Urgent measures were taken including hyaluronidase enzyme injection, vigorous messaging, and systemic steroids. Eight weeks later, the extraocular motility has fully recovered; however, the consequences of ischemia on the anterior and posterior ocular segments persisted. CONCLUSIONS AND IMPORTANCE: Describing a major refractory complication following injecting hyaluronic acid dermal filler. Prompt intervention including the use retro or peribulbar injection of hyaluronidase has a little impact when it comes to reversing ocular sequalae. Therefore, injectors should be aware of facial danger zones that could potentially lead to this devastating outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.