ReviewSpine surgery and related research2021
Lumbar Spinal Canal Stenosis from the Perspective of Locomotive Syndrome and Metabolic Syndrome: A Narrative Review.
Review in Spine surgery and related research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- Neurological Phenotype and MRI Severity as Predictors of Duloxetine Response in Lumbar Spinal Stenosis: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Comparative analysis of surgically treated degenerative cervical and lumbar spine diseases using multiple clinical aging indices.BMC musculoskeletal disorders · 2025Article
- Comparison of clinical outcomes between biportal and uniportal full-endoscopy techniques in lumbar spinal stenosis with bilateral symptoms.World journal of orthopedics · 2025Article
- Age diversity among older surgically treated patients with lumbar spinal stenosis: a retrospective comparative study of early and late older adults.BMC musculoskeletal disorders · 2025Article
- Possible negative impact of polypharmacy on surgical outcomes in older patients with lumbar spinal stenosis.Geriatrics & gerontology international · 2025Article
- Association between lifestyle-related factors and low back pain: Evidence from a Japanese population-based study.PloS one · 2025Article
- Unilateral biportal endoscopy for the treatment of symptomatic spinal epidural lipomatosis: a case report and literature review.Frontiers in surgery · 2025Article
- Unveiling therapeutic targets for spinal stenosis from genetic insights: a Mendelian randomization analysis.Scientific reports · 2024Article
- Association of visceral fat area with early-stage locomotive syndrome across various age groups: a cross-sectional study.Scientific reports · 2024Article
- Medication-based profiling of older orthopedic patients: a multicenter cross-sectional study.BMC geriatrics · 2024Article
- Safety and feasibility of in-hospital autonomous transportation using a driverless mobility for patients with musculoskeletal disorders: preliminary clinical study to achieve mobility as a service in medical care.BMC musculoskeletal disorders · 2024Article
- The Impact of Frailty on Surgical Outcome of Patients with Lumbar Spinal Canal Stenosis.Spine surgery and related research · 2024Article
- [Clinical research progress of spinal epidural lipomatosis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023Review
- High prevalence of lumbar spinal stenosis in cases of idiopathic normal-pressure hydrocephalus affects improvements in gait disturbance after shunt operation.World neurosurgery: X · 2023Article
- Could Spinal Epidural Lipomatosis Be the Hallmark of Metabolic Syndrome on the Spine? A Literature Review with Emphasis on Etiology.Diagnostics (Basel, Switzerland) · 2023Review
- Gut-spine axis: a possible correlation between gut microbiota and spinal degenerative diseases.Frontiers in microbiology · 2023Review
- Relationship between changes in physical function parameters and Roland-Morris disability questionnaire score after decompression surgery for lumbar spinal canal stenosis.Nagoya journal of medical science · 2022Article
- Is there an association between lumbosacral epidural lipomatosis and lumbosacral epidural steroid injections? A comprehensive narrative literature review.North American Spine Society journal · 2022Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
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Abstract
Patients with lumbar spinal canal stenosis (LSS) have impaired activities of daily living because of pain or motor paralysis, but no effective preventive treatment is currently available. The number of patients with LSS is predicted to continually increase as the average age of the global population increases. To provide a conceptual framework for improving healthy life expectancy, the Japanese Orthopaedic Association introduced the concept of locomotive syndrome, to which LSS is related. Ours and other studies have shown that LSS exacerbates locomotive syndrome and that surgical treatment is one method for improving it. Furthermore, we propose that the two-step test, a locomotive syndrome risk test, is effective for assessing the risk for falls and severity of LSS. Meanwhile, lumbar spinal epidural lipomatosis (LSEL), which is a manifestation of LSS, has been shown to be related to metabolic syndrome. Previous studies have suggested that the whole LSS can be also associated with metabolic syndrome. Although locomotive syndrome is very different from metabolic syndrome, which involves lipid metabolism, these two syndromes overlap, such as in LSS. Conducting research on LSS from the perspectives of both locomotive syndrome and metabolic syndrome may lead to novel methods for prevention and treatment of LSS and, conversely, may yield clues for resolving symptoms of the two syndromes. This review provides an overview of LSS from the perspective of locomotive syndrome and metabolic syndrome, along with findings from our research group.
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