ArticleAnnals of translational medicine2021
The role of magnification correction in macular vessel density assessment: a contralateral eye study in anisometropia patients.
Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Normative Optical Coherence Tomography Angiography Metrics of Macular Vessel Density and Foveal Avascular Zone in Healthy Children.Journal of clinical medicine · 2025Article
- Retinal and Choroidal Vascular Biomarkers Are Correlated With the Degree of Myopia.Translational vision science & technology · 2025Article
- Interocular comparison of peripapillary retinal nerve fiber layer thickness and vasculature in non-pathological myopia with anisometropia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Correcting magnification error in foveal avascular zone area measurements of optical coherence tomography angiography images with estimated axial length.Eye and vision (London, England) · 2022Article
- Investigation of Macular Structural and Microcirculatory Characteristics of Posterior Staphyloma in High Myopic Eyes by Swept Source Optical Coherence Tomography Angiography.Frontiers in physiology · 2022Article
- Normative Data and Determinants of Macular, Disc, and Peripapillary Vascular Density in Healthy Myopic Children Using Optical Coherence Tomography Angiography.Frontiers in medicine · 2022Article
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Authors and funding
6 authors.
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Abstract
backgroundInvestigating the impact of magnification correction in macular vessel density using optical coherence tomography angiography (OCTA) in patients with anisometropia.
methodsCross-sectional study. Totally 47 patients (11 male, 36 female) aged >18 years with high myopia were analyzed. All patients underwent evaluation of visual acuity, subjective refraction, and axial length. Anisometropia (n=37) was defined as a refraction difference between paired eyes ≥0.75 D. The control group (n=10) consisted patients with a refraction difference ≤0.5 D. Superficial vessel density was performed using 3 mm × 3 mm Cirrus-HD OCTA protocol. The vessel length density (VLD) and foveal avascular zone area (FAZA) were analyzed before and after magnification correction using Bennett's formula.
resultsThe mean spherical equivalent (SE) was -10.54±3.47 D in the more myopic eye and -8.05±3.47 D in the contralateral eye (P<0.001). Before magnification correction, the mean perfusion density (PD) and VLD were both significantly lower in the more myopic eyes. After magnification correction, the VLD and PD did not differ between paired eyes. No statistical difference was found in terms of the FAZA between paired eyes regardless of magnification correction. The magnification-induced differences in both VLD and PD were positively correlated with the difference in SE (both r=0.86, P<0.001).
conclusionsIn OCTA analysis, magnification correction should be performed to reduce refraction error-induced image error, which deserves attention in the clinical application.
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