Evidence map›Paper›PMID 33842494›Full record

ArticleFrontiers in medicine2021

Clinical Characteristics of Severe COVID-19 Patients Admitted to an Intensive Care Unit in Lombardy During the Italian Pandemic.

Matteo Briguglio, Tiziano Crespi, Fabio Pino, Marco Mazzocchi, Mauro Porta, Elena De Vecchi, Giuseppe Banfi, Paolo Perazzo

Abstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Major coagulation disorders and parameters in COVID-19 patients.European journal of medical research · 2022
    Review
  6. Article
  7. Article
  8. Review
  9. Clinical characteristics and treatment outcomes of severe (ICU) COVID-19 patients in Saudi Arabia: A single centre study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  10. Antithrombin and Its Role in Host Defense and Inflammation.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matteo BriguglioIRCCS Orthopedic Institute Galeazzi, Scientific Direction, Milan, Italy.
Tiziano CrespiIntensive Care Unit, IRCCS Orthopedic Institute Galeazzi, Milan, Italy.
Fabio PinoIntensive Care Unit, IRCCS Orthopedic Institute Galeazzi, Milan, Italy.
Marco MazzocchiIntensive Care Unit, IRCCS Orthopedic Institute Galeazzi, Milan, Italy.
Mauro PortaNeurology Unit, IRCCS Orthopedic Institute Galeazzi, Milan, Italy.
Elena De VecchiLaboratory of Clinical Chemistry and Microbiology, IRCCS Orthopedic Institute Galeazzi, Milan, Italy.
Giuseppe BanfiIRCCS Orthopedic Institute Galeazzi, Scientific Direction, Milan, Italy.
Paolo PerazzoIntensive Care Unit, IRCCS Orthopedic Institute Galeazzi, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Italy was one of the worst affected European countries during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. More than 50% of Italian cases occurred in the northern region of Lombardy, where the saturation of health services between March and April 2020 forced hospitals to allocate patients according to available resources. Eighteen severe coronavirus disease 2019 (COVID-19) patients were admitted to our hospital needing intensive support. Given the disease fatality, we investigated the patients' characteristics to identify mortality predictors. We counted seven deaths from multiple organ failure, two from septic shock, and two from collapsed lungs. The maximum case fatality was observed in patients who contracted SARS-CoV-2 in hospitals. The fatal outcome was associated with the following baseline characteristics: polymorbidity (OR 2.519,

Indexed as

anesthesiaCOVID-19infectionintensive careintubationSARS-CoV-2sepsissystemic inflammatory response syndrome

Identifiers

PMID33842494
PMCPMC8027304

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.