Evidence map›Paper›PMID 33842489›Full record

ArticleFrontiers in cell and developmental biology2021

Sycp1 Is Not Required for Subtelomeric DNA Double-Strand Breaks but Is Required for Homologous Alignment in Zebrafish Spermatocytes.

Yukiko Imai, Kenji Saito, Kazumasa Takemoto, Fabien Velilla, Toshihiro Kawasaki, Kei-Ichiro Ishiguro, Noriyoshi Sakai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. The DNA mismatch repair protein Msh4 is essential for meiosis of male but not for female in zebrafish.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
    Article
  4. Article
  5. Long Non-Coding RNAInternational journal of molecular sciences · 2025
    Article
  6. Deletion ofBiology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Meiotic Chromosome Dynamics in Zebrafish.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yukiko ImaiDepartment of Gene Function and Phenomics, National Institute of Genetics, Mishima, Japan.
Kenji SaitoDepartment of Gene Function and Phenomics, National Institute of Genetics, Mishima, Japan.
Kazumasa TakemotoDepartment of Gene Function and Phenomics, National Institute of Genetics, Mishima, Japan.
Fabien VelillaDepartment of Gene Function and Phenomics, National Institute of Genetics, Mishima, Japan.
Toshihiro KawasakiDepartment of Gene Function and Phenomics, National Institute of Genetics, Mishima, Japan.
Kei-Ichiro IshiguroDepartment of Chromosome Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan.
Noriyoshi SakaiDepartment of Gene Function and Phenomics, National Institute of Genetics, Mishima, Japan.
National Institute of Genetics · JPKumamoto University · JPThe Graduate University for Advanced Studies, SOKENDAI · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In meiotic prophase I, homologous chromosomes are bound together by the synaptonemal complex, in which two axial elements are connected by transverse filaments and central element proteins. In human and zebrafish spermatocytes, homologous recombination and assembly of the synaptonemal complex initiate predominantly near telomeres. In mice, synapsis is not required for meiotic double-strand breaks (DSBs) and homolog alignment but is required for DSB repair; however, the interplay of these meiotic events in the context of peritelomeric bias remains unclear. In this study, we identified a premature stop mutation in the zebrafish gene encoding the transverse filament protein Sycp1. In

Indexed as

meiosisrecombinationSycp1synapsissynaptonemal complexzebrafish

Identifiers

PMID33842489
PMCPMC8033029
OpenAlexW3143821600

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.