Evidence map›Paper›PMID 33842015›Full record

ReviewJournal of advanced research2021

Mapping metabolome changes in

Amal A Maamoun, Radwa H El-Akkad, Mohamed A Farag

Open access · goldAbstract readReview
In one paragraph

Review in Journal of advanced research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. The Discovery of Potential Repellent Compounds forInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Phytochemical composition ofFood chemistry: X · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. How DoesFoods (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Review
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  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Amal A MaamounDepartment of Pharmacognosy, National Research Centre, 33 El Buhouth St., P.O. 12622 (ID:60014618), Cairo, Egypt.
Radwa H El-AkkadDepartment of Pharmacognosy, National Research Centre, 33 El Buhouth St., P.O. 12622 (ID:60014618), Cairo, Egypt.
Mohamed A FaragPharmacognosy Department, College of Pharmacy, Cairo University, Kasr el Aini St., P.B. 11562, Cairo, Egypt.
National Research Centre · EGAmerican University in Cairo · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction

objectivesComprehensively compare the metabolites profile of YF and MF to give insight on how maturation stage affects chemical composition.

methodsMass-based metabolomics comprising GC/MS and UHPLC/MS were adopted in this study targeting its volatile and non-volatile metabolites coupled with chemometrics to rationalize for the differences.

resultsA total of 53 volatile metabolites were identified via headspace solid phase microextraction (SPME) comprising 66.2% aldehydes/furans, 51.6% alcohols, 38.2% ketones, 15.1% acids and 10.1% aromatics of which aldehydes/ furans were dominant at both fruit stages. Young fruit was in general more erniched in metabolites as revealed from UHPLC/MS and GC/MS analyses. The YF group encompassed higher levels of short chain alcohols (1-octen-3-ol) and aldehydes ((E)-2-hexenal and cucumber aldehyde) in addition to terpenoids (linalool). In contrast, fatty acids (octanoic acid) predominated MF specimens. UHPLC/MS analysis revealed for several oleanene triterpene glycosides as major secondary bioactive compounds, dihydroxy-oxo-oleanenoic acid glycoside found more abundant in YF versus MF as revealed from multivariate data analyses.

conclusionsOur results reveal for the distinct metabolite changes in

Indexed as

GC/MSLuffa aegyptiacaMetabolomicsSPMEUHPLC/MS

Identifiers

PMID33842015
PMCPMC8020157
OpenAlexW2981951705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.