Evidence map›Paper›PMID 33842005›Full record

ArticleJournal of advanced research2021

Endogenous sulfur dioxide is a novel inhibitor of hypoxia-induced mast cell degranulation.

Lulu Zhang, Hongfang Jin, Yunjia Song, Selena Ying Chen, Yi Wang, Yan Sun, Chaoshu Tang, Junbao Du, Yaqian Huang

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Vascular smooth muscle cell-derived SOFrontiers in pharmacology · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. A Whiff of Sulfur: One Wind a Day Keeps the Doctor Away.Antioxidants (Basel, Switzerland) · 2022
    Review
  6. Review
  7. Endothelial Cell-Derived SOOxidative medicine and cellular longevity · 2021
    Article
  8. Sulphenylation of CypD at Cysteine 104: A Novel Mechanism by Which SOFrontiers in cell and developmental biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Lulu ZhangDepartment of Pediatrics, Peking University First Hospital, Beijing, China.
Hongfang JinDepartment of Pediatrics, Peking University First Hospital, Beijing, China.
Yunjia SongDepartment of Pediatrics, Peking University First Hospital, Beijing, China.
Selena Ying ChenDivision of Biological Sciences, University of California, San Diego, La Jolla, CA, United States.
Yi WangDepartment of Pediatrics, Peking University First Hospital, Beijing, China.
Yan SunDepartment of Pediatrics, Peking University First Hospital, Beijing, China.
Chaoshu TangDepartment of Physiology and Pathophysiology, Peking University Health Science Centre, Beijing, China.
Junbao DuDepartment of Pediatrics, Peking University First Hospital, Beijing, China.
Yaqian HuangDepartment of Pediatrics, Peking University First Hospital, Beijing, China.
Peking University · CNPeking University First Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNUniversity of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Mast cell (MC) degranulation is an important step in the pathogenesis of inflammatory reactions and allergies; however, the mechanism of stabilizing MC membranes to reduce their degranulation is unclear. Methods: SO Objectives: To exam whether an endogenous sulfur dioxide (SO Results: We firstly show the existence of the endogenous SO Conclusion: SO

Indexed as

Cell DegranulationAnimalsAspartate Aminotransferasesbeta-N-AcetylhexosaminidasesCyclic AMPDown-RegulationHumansHypoxiaInflammationLungMaleMast CellsRatsRats, WistarSignal TransductionSulfur DioxideAspartate Aminotransferasesbeta-N-AcetylhexosaminidasesCyclic AMPSulfur DioxidecAMPDegranulationEndogenous sulfur dioxideMast cellsStabilization

Identifiers

PMID33842005
PMCPMC8020161
OpenAlexW3084150590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.