Evidence map›Paper›PMID 33841919›Full record

ReviewEFORT open reviews2021

Defining mechanical instability in tuberculosis of the spine: a systematic review.

Kaustubh Ahuja, Syed Ifthekar, Samarth Mittal, Gagandeep Yadav, Bhaskar Sarkar, Pankaj Kandwal

Open access · goldAbstract readReview
In one paragraph

Review in EFORT open reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Deep learning radiomics model based on contrast-enhanced MRI for distinguishing between tuberculous spondylitis and pyogenic spondylitis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Utility of clinicoradiological, microbiological, histopathological, and molecular methods in the diagnosis of spinal tuberculosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kaustubh AhujaDepartment of Orthopaedic Surgery, All India Institute of Medical Sciences, Uttarakhand, India.ORCID https://orcid.org/0000-0003-1344-9889
Syed IfthekarDepartment of Orthopaedic Surgery, All India Institute of Medical Sciences, Uttarakhand, India.
Samarth MittalDepartment of Orthopaedic Surgery, All India Institute of Medical Sciences, Uttarakhand, India.
Gagandeep YadavDepartment of Orthopaedic Surgery, All India Institute of Medical Sciences, Uttarakhand, India.
Bhaskar SarkarDepartment of Orthopaedic Surgery, All India Institute of Medical Sciences, Uttarakhand, India.
Pankaj KandwalDepartment of Orthopaedic Surgery, All India Institute of Medical Sciences, Uttarakhand, India.ORCID https://orcid.org/0000-0002-8801-6909
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the years, a number of authors have used different working definitions of instability in tuberculosis of the spine (TB spine). However, no clear consensus exists to define instability in TB spine. The current systematic review addresses the question 'What defines instability in TB spine'?A comprehensive medical literature search was carried out to identify all the studies which defined instability in the setting of spinal TB. The extracted data included the clinical, X-ray and CT or MRI-based definitions.The current review identified lesser age, junctional region of the spine, mechanical pain and 'instability catch', kyphotic deformity above 40 degrees, pan-vertebral or bilateral facetal involvement and multifocal contiguous disease involving more than three vertebrae as predictors for spinal instability in the dorso-lumbar spine.Cervical kyphosis more than 30 degrees and facetal or pan-vertebral involvement were found to be the factors used to define instability in subaxial cervical spine.With respect to C1-C2 TB spine, migration of the tip of the odontoid above the McRae or McGregor line or anterior translation of C1 over C2 were considered as determinants for instability.Although definitive conclusions could not be drawn due to lack of adequate evidence, the authors identified factors which may contribute towards instability in TB spine. Cite this article:

Indexed as

deformityinstabilitykyphosisspinal tuberculosissystematic reviewtuberculosis

Identifiers

PMID33841919
PMCPMC8025706
OpenAlexW3134614673

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.