Evidence map›Paper›PMID 33841881›Full record

ArticleMaterials horizons2020

Triggered micropore-forming bioprinting of porous viscoelastic hydrogels.

Guangyu Bao, Tao Jiang, Hossein Ravanbakhsh, Alicia Reyes, Zhenwei Ma, Mitchell Strong, Huijie Wang, Joseph M Kinsella, Jianyu Li, Luc Mongeau

Abstract read
In one paragraph

Article in Materials horizons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

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  13. Multiscale embedded printing of engineered human tissue and organ equivalents.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guangyu BaoDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.
Tao JiangDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.
Hossein RavanbakhshDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.
Alicia ReyesDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.
Zhenwei MaDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.
Mitchell StrongDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.
Huijie WangDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.
Joseph M KinsellaDepartment of Bioengineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.
Jianyu LiDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.
Luc MongeauDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.

Funding

Fluid Structure Interactions Within the Human LarynxR01DC005788 · NIDCD · PURDUE UNIVERSITY WEST LAFAYETTE · PI MONGEAU, LUC · 2003 to 2018
$6.4M
A Hydrogel-Based Cellular Model of the Human Vocal FoldR01DC014461 · NIDCD · UNIVERSITY OF DELAWARE · PI Xinqiao Jia · 2016 to 2026
$6.2M
Bioprintable composite materials and microfluidic tools for vocal fold restoration and repairR01DC018577 · NIDCD · MCGILL UNIVERSITY · PI MONGEAU, LUC · 2021 to 2025
$2.5M
NIDCD NIH HHS R01 DC005788NIDCD NIH HHS R01 DC014461NIDCD NIH HHS R01 DC018577
6 · The paper itself

Abstract

Cell-laden scaffolds of architecture and mechanics that mimic those of the host tissues are important for a wide range of biomedical applications but remain challenging to bioprint. To address these challenges, we report a new method called triggered micropore-forming bioprinting. The approach can yield cell-laden scaffolds of defined architecture and interconnected pores over a range of sizes, encompassing that of many cell types. The viscoelasticity of the bioprinted scaffold can match that of biological tissues and be tuned independently of porosity and stiffness. The bioprinted scaffold also exhibits superior mechanical robustness despite high porosity. The bioprinting method and the resulting scaffolds support cell spreading, migration, and proliferation. The potential of the 3D bioprinting system is demonstrated for vocal fold tissue engineering and as an

Indexed as

Biocompatible MaterialsBioprintingHumansHydrogelsIn Vitro TechniquesNeoplasmsPorosityPrinting, Three-DimensionalRegenerative MedicineTissue EngineeringTissue ScaffoldsBiocompatible MaterialsHydrogels

Identifiers

PMID33841881
PMCPMC8030731

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.