Evidence map›Paper›PMID 33841817›Full record

ArticleFood science & nutrition2021

Hypoglycemic and hypolipidemic activities of phlorizin from

Wei Zhang, Shiqi Chen, Hualin Fu, Gang Shu, Huaqiao Tang, Xiaoling Zhao, Yang Chen, Xiangyue Huang, Ling Zhao, Lizi Yin and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
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  6. Article
  7. Bioactive Substances and Biological Functions inMolecules (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Wei ZhangDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Shiqi ChenDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.ORCID https://orcid.org/0000-0002-9253-9833
Hualin FuDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Gang ShuDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Huaqiao TangDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Xiaoling ZhaoDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Yang ChenDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Xiangyue HuangDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Ling ZhaoDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Lizi YinDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Cheng LvDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Juchun LinDepartment of Pharmacy College of Veterinary Medicine Sichuan Agricultural University Chengdu China.
Sichuan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to investigate the hypoglycemic and hypolipidemic effects of phlorizin on sweet tea in rats with diabetes. Diabetic rat model was established by feeding with HFD (high-fat diet) and then treating with intraperitoneal injection of STZ (streptozocin). The experiments were divided into therapeutic and preventive experiments. In both experiments, rats were divided into normal, diabetic control, positive control, and phlorizin groups. Symptoms of diabetes, fasting blood glucose (FBG) levels, serum lipid parameters, and pathological changes in the pancreas and liver were evaluated. It was found that the symptoms of diabetes were improved by phlorizin treatment. In addition, phlorizin could decrease FBG, improve serum lipid levels, protect against damaged pancreas islet, and decrease fat deposition in hepatic cells. These effects of phlorizin can be shown only attain to a certain dosage. It can be concluded that phlorizin has the therapeutic and preventive effects on hyperlipidemia and hyperglycemia in diabetes rats.

Indexed as

diabeteshyperglycemiahyperlipidemiaLithocarpus polystachyus Rehd.phlorizinSD rats

Identifiers

PMID33841817
PMCPMC8020910
OpenAlexW3126710221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.