Evidence map›Paper›PMID 33841667›Full record

ArticleAmerican journal of translational research2021

STAT5 inhibitor attenuates atherosclerosis via inhibition of inflammation: the role of STAT5 in atherosclerosis.

Xiaodong Wang, Xiaoji Ding, Jin Yan, Ziying Lu, Haoyang Cao, Xiaolong Ni, Yin Ying

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  5. Review
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  8. An inflammatory transcriptomic signature in psoriasis associates with future cardiovascular events.Journal of the European Academy of Dermatology and Venereology : JEADV · 2023
    Article
  9. Article
  10. Review
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  13. Interleukin-22: a potential therapeutic target in atherosclerosis.Molecular medicine (Cambridge, Mass.) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiaodong WangSino-German Joint Research Center of Vascular Surgery, Zhejiang Academy of Traditional Chinese Medicine Hangzhou 310012, Zhejiang, China.
Xiaoji DingDepartment of Pharmacy, Zhejiang Academy of Traditional Chinese Medicine Hangzhou 310012, Zhejiang, China.
Jin YanDepartment of Vascular Surgery, Tongde Hospital of Zhejiang Province Hangzhou 310012, Zhejiang, China.
Ziying LuDepartment of Vascular Surgery, Tongde Hospital of Zhejiang Province Hangzhou 310012, Zhejiang, China.
Haoyang CaoDepartment of Vascular Surgery, Tongde Hospital of Zhejiang Province Hangzhou 310012, Zhejiang, China.
Xiaolong NiDepartment of Vascular Surgery, Tongde Hospital of Zhejiang Province Hangzhou 310012, Zhejiang, China.
Yin YingDepartment of Pharmacy, Zhejiang Academy of Traditional Chinese Medicine Hangzhou 310012, Zhejiang, China.
Tongde Hospital of Zhejiang Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a chronic inflammatory disease driven by lipids, which occurs preferentially in the branches or curved areas of the middle and large arteries, contributing to increased morbidity and mortality of cardiovascular disease. Recently, it has been reported that STAT5 and its regulated immune response are closely related to non-tumor diseases. However, the role of STAT5 in the development of atherosclerosis remains unknown. In this study, atherosclerosis was induced by high-fat diet (HFD) in ApoE

Indexed as

atherosclerosisinflammationSignal transducer and activator of transcription 5

Identifiers

PMID33841667
PMCPMC8014372
OpenAlexW3154737295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.