Evidence map›Paper›PMID 33841664›Full record

ArticleAmerican journal of translational research2021

From hair to pancreas: transplanted hair follicle mesenchymal stem cells express pancreatic progenitor cell markers in a rat model of acute pancreatitis.

Xiaoli Sun, Yang Gao, Haoyuan Chen, Ningning Yang, Yichi Zhang, Qi Liu, Yanan Jiang, Shizhu Jin

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiaoli SunDepartment of Gastroenterology and Hepatology, The Second Affiliated Hospital, Harbin Medical University Harbin 150086, P. R. China.
Yang GaoDepartment of Gastroenterology and Hepatology, The Second Affiliated Hospital, Harbin Medical University Harbin 150086, P. R. China.
Haoyuan ChenDepartment of Gastroenterology and Hepatology, The Second Affiliated Hospital, Harbin Medical University Harbin 150086, P. R. China.
Ningning YangDepartment of Gastroenterology and Hepatology, The Second Affiliated Hospital, Harbin Medical University Harbin 150086, P. R. China.
Yichi ZhangDepartment of Gastroenterology and Hepatology, The Second Affiliated Hospital, Harbin Medical University Harbin 150086, P. R. China.
Qi LiuDepartment of Gastroenterology and Hepatology, The Second Affiliated Hospital, Harbin Medical University Harbin 150086, P. R. China.
Yanan JiangDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University Harbin 150081, P. R. China.
Shizhu JinDepartment of Gastroenterology and Hepatology, The Second Affiliated Hospital, Harbin Medical University Harbin 150086, P. R. China.
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute pancreatitis (AP) is commonly accompanied by intense pain and is associated with high mortality rates. However, the effectiveness of existing therapeutic approaches remains unsatisfactory. Stem cell therapy, which can promote the regeneration of damaged tissue and alleviate systemic inflammatory responses, has brought new possibility for patients suffering from AP. In particular, hair follicle-derived mesenchymal stem cells (HF-MSCs) are proposed as a suitable cell source for treating pancreatic diseases, but further research on their effectiveness, safety, and underlying mechanisms is warranted for clinical implementation. In this work, the therapeutic potential of HF-MSC transplantation was studied in an L-arginine-induced AP rat model. HF-MSCs were extracted from infant Sprague-Dawley (SD) rats, expanded

Indexed as

acute pancreatitiscell transplantationdifferentiationHair follicle mesenchymal stem cellshoming

Identifiers

PMID33841664
PMCPMC8014427
OpenAlexW3154851145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.