Evidence map›Paper›PMID 33841573›Full record

ArticleOncology letters2021

lncRNA transcription factor 7 is related to deteriorating clinical features and poor prognosis in multiple myeloma, and its knockdown suppresses disease progression by regulating the miR-203-mediated Jagged1-Notch1 signaling pathway.

Haiyan Liu, Yaodong Shen, Ya Xu, Li Wang, Chenlu Zhang, Yijing Jiang, Lemin Hong, Hongming Huang, Hong Liu

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Long non‑coding RNAs in multiple myeloma (Review).International journal of oncology · 2023
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Haiyan LiuDepartment of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.
Yaodong ShenDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Ya XuDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Li WangDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Chenlu ZhangDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Yijing JiangDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Lemin HongDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Hongming HuangDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Hong LiuDepartment of Hematology, The Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.
Affiliated Hospital of Nantong University · CNNantong University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) remains a challenge to treat, and its precise pathogenic mechanisms have not been fully clarified. The present study aimed to evaluate the relation between long non-coding RNA transcription factor 7 (lnc-TCF7) and clinical features, as well as the prognosis of patients with MM, and to determine the effects of lnc-TCF7-knockdown on the regulation (and regulatory mechanisms) of MM progression. lnc-TCF7 expression was detected in the bone marrow plasma cells of 86 patients with MM and 30 healthy controls. In patients with MM, the clinical data were collected, and event-free survival (EFS) and overall survival (OS) analyses were conducted.

Indexed as

Jagged1lnc-TCF7miR-203multiple myelomaNotch1

Identifiers

PMID33841573
PMCPMC8020383
OpenAlexW3136794820

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.