Evidence map›Paper›PMID 33841419›Full record

ArticleFrontiers in immunology2021

Damage-Induced Calcium Signaling and Reactive Oxygen Species Mediate Macrophage Activation in Zebrafish.

Tamara Sipka, Romain Peroceschi, Rahma Hassan-Abdi, Martin Groß, Felix Ellett, Christina Begon-Pescia, Catherine Gonzalez, Georges Lutfalla, Mai Nguyen-Chi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 44 citations in OpenAlex.

  1. Commensal skin bacteria interact with the innate immune system to promote tail regeneration in Xenopus laevis tadpoles.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
    Article
  2. Calcium Signaling in Macrophages During a Wound Response In Vivo.International journal of molecular sciences · 2026
    Article
  3. Intracellular pH dynamics promotes zebrafish larval tail regeneration.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. A Novel Cargo Delivery System-AnCar-ExoAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Sprayed PAA-CaORegenerative biomaterials · 2023
    Article
  16. Review
  17. Wound Healing Insights from Flies and Fish.Cold Spring Harbor perspectives in biology · 2022
    Review
  18. Review
  19. Article
  20. The Macrophage Iron Signature in Health and Disease.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Tamara SipkaLPHI, Univ Montpellier, CNRS, Montpellier, France.
Romain PeroceschiLPHI, Univ Montpellier, CNRS, Montpellier, France.
Rahma Hassan-AbdiLPHI, Univ Montpellier, CNRS, Montpellier, France.
Martin GroßLPHI, Univ Montpellier, CNRS, Montpellier, France.
Felix EllettBateson Centre and Department of Infection and Immunity, University of Sheffield, Sheffield, United Kingdom.
Christina Begon-PesciaLPHI, Univ Montpellier, CNRS, Montpellier, France.
Catherine GonzalezLPHI, Univ Montpellier, CNRS, Montpellier, France.
Georges LutfallaLPHI, Univ Montpellier, CNRS, Montpellier, France.
Mai Nguyen-ChiLPHI, Univ Montpellier, CNRS, Montpellier, France.
Centre National de la Recherche Scientifique · FRUniversité de Montpellier · FRHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immediately after a wound, macrophages are activated and change their phenotypes in reaction to danger signals released from the damaged tissues. The cues that contribute to macrophage activation after wounding

Indexed as

Animal FinsAnimalsCalcium SignalingCell DifferentiationLarvaMacrophage ActivationMacrophagesNF-kappa BReactive Oxygen Speciessrc-Family KinasesWound HealingWounds and InjuriesZebrafishZebrafish ProteinsLyn protein, zebrafishNF-kappa BReactive Oxygen Speciessrc-Family KinasesZebrafish Proteinscalciummacrophage activationreactive oxygen specieswound healingzebrafish

Identifiers

PMID33841419
PMCPMC8032883
OpenAlexW3144062749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.