ReviewFrontiers in neurology2021
The Essential Tremors: Evolving Concepts of a Family of Diseases.
Review in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed.
- The spectrum of square wave jerks in essential tremor: an exploratory study.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Essential Tremor Cases with Subtle Cerebellar Pathology: A Systematic Study of Postmortem Cerebellar Changes.Cerebellum (London, England) · 2026Article
- Similar DTI-ALPS metrics in Parkinson's disease and essential tremor: a cross-sectional comparative analysis.Neuroradiology · 2026Article
- Longitudinal Intention Tremor Trajectories in Essential Tremor: A Comment.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- Underlying Tremor Improvement with Consistent Use of Transcutaneous Afferent Patterned Stimulation in Patients with Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- The cerebellar involvement in essential tremor: the connecting roads.Arquivos de neuro-psiquiatria · 2025Review
- The relation between upper limbs action tremor asymmetry, midline tremor and gait disorders in essential tremor: an exploratory study.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Quantum-classical deep learning hybrid architecture with graphene-printed low-cost capacitive sensor for essential tremor detection.Scientific reports · 2025Article
- Cognitive trajectories in older adults with essential tremor.Journal of the International Neuropsychological Society : JINS · 2025Article
- Epidemiology and treatment patterns of essential tremor: a retrospective cohort analysis in Germany.Frontiers in neurology · 2025Article
- On the Effect of Vibrotactile Stimulation in Essential Tremor.Healthcare (Basel, Switzerland) · 2024Article
- Dynamic functional changes upon thalamotomy in essential tremor depend on baseline brain morphometry.Scientific reports · 2024Article
- Six Myths and Misconceptions about Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024Review
- Gene Expression Analysis of Laser-Captured Purkinje Cells in the Essential Tremor Cerebellum.Cerebellum (London, England) · 2023Article
- Upper Limb Function but Not Proprioception is Impaired in Essential Tremor: A Between-Groups Study and Causal Mediation Analysis.Tremor and other hyperkinetic movements (New York, N.Y.) · 2023Article
- Essential tremor plus rest tremor: current concepts and controversies.Journal of neural transmission (Vienna, Austria : 1996) · 2022Review
- Essential Tremor: Five New Things.Neurology. Clinical practice · 2022Article
- Graph Theoretical Analysis of Structural Covariance Reveals the Relevance of Visuospatial and Attentional Areas in Essential Tremor Recovery After Stereotactic Radiosurgical Thalamotomy.Frontiers in aging neuroscience · 2022Article
- Is essential tremor a degenerative disorder or an electric disorder? Degenerative disorder.International review of neurobiology · 2022Article
- What's in a Name? Nomenclature of essential tremor: Syndrome or family of diseases?International review of neurobiology · 2022Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
The past 10 years has seen a remarkable advance in our understanding of the disease traditionally referred to as "essential tremor" (ET). First, the clinical phenotype of ET has been expanded from that of a bland, unidimensional, and monosymptomatic entity to one with a host of heterogeneous features. These features include a broader and more nuanced collection of tremors, non-tremor motor features (e.g., gait abnormalities) and a range of non-motor features, including cognitive, psychiatric, sleep, and other abnormalities. The natural history of these features, as well as their relationships with one another and with disease duration and severity, are better appreciated than they were previously. Studies of disease etiology have identified a number of candidate genes as well as explored several environmental determinants of disease. In addition, the decade has seen the beginnings and expansion of rigorous postmortem studies that have identified and described the postmortem changes in the brains of patients with ET. This emerging science has given rise to a new notion that the disease, in many cases, is one of cerebellar system degeneration. Across all of these studies (clinical, etiological, and pathophysiological) is the observation that there is heterogeneity across patients and that "essential tremor" is likely not a single disease but, rather, a family of diseases. The time has come to use the more appropriate terminology, "the essential tremors," to fully describe and encapsulate what is now apparent. In this paper, the author will review the clinical, etiological, and pathophysiological findings, referred to above, and make the argument that the terminology should evolve to reflect advances in science and that "the essential tremors" is a more scientifically appropriate term.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.