ArticleFrontiers in neurology2021
Decreased Functional Connectivity of the Primary Visual Cortex and the Correlation With Clinical Features in Patients With Intermittent Exotropia.
Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Evaluating the image quality and brain microstructural exploration of mean apparent propagator-MRI-a pilot study.BMC medical imaging · 2026Article
- Functional and Metabolic Abnormalities in Primary Visual Cortex and Frontal Eye Fields and Candidate Biomarkers of Acute Acquired Comitant Esotropia.Investigative ophthalmology & visual science · 2026Article
- Mean Apparent Propagator MRI: A Potential Imaging Biomarker of Brain Microstructural Alterations in Basic-Type Intermittent Exotropia.Investigative ophthalmology & visual science · 2026Article
- Effects of Home-Based Antisuppression and Binocular Integration Training in Patients with Intermittent Exotropia: A Retrospective Study.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Reading ability in children with intermittent exotropia and its association with binocular visual function and visual information processing capability.BMC ophthalmology · 2025Article
- Machine Learning-Based Identification of Children With Intermittent Exotropia Using Multiple Resting-State Functional Magnetic Resonance Imaging Features.Brain and behavior · 2025Article
- Altered static and dynamic functional connectivity in childhood basic-type intermittent exotropia.Brain communications · 2025Article
- Gait dynamics and brain function abnormalities in Parkinson's disease with freezing of gait: a clinical study using resting-state fMRI and wearable devices.Frontiers in neuroscience · 2025Article
- Alterations of interhemispheric functional connectivity in patients with hypertensive retinopathy using voxel-mirrored homotopic connectivity: a resting state fMRI study.International journal of ophthalmology · 2025Article
- Altered functional connectivity of resting-state networks and the correlation with clinical characteristics in intermittent exotropia adult patients: a resting-state magnetic resonance imaging study.BMC ophthalmology · 2024Article
- Abnormal occipital and frontal activity during voluntary convergence in intermittent exotropia: A task-fMRI study.Heliyon · 2024Article
- Impact of prenatal marijuana exposure on adolescent brain structural and functional connectivity and behavioural outcomes.Brain communications · 2024Article
- Altered Large-Scale Resting-State Functional Network Connectivity in Convergence Insufficiency Young Adults Compared With Binocularly Normal Controls.Investigative ophthalmology & visual science · 2023Article
- Alterations of large-scale functional network connectivity in patients with infantile esotropia before and after surgery.Brain and behavior · 2023Article
- Altered Temporal Dynamics of the Amplitude of Low-Frequency Fluctuations in Comitant Exotropia Patients.Frontiers in human neuroscience · 2022Article
- Local structural-functional connectivity decoupling of caudate nucleus in infantile esotropia.Frontiers in neuroscience · 2022Article
- Abnormal cortical morphology in children and adolescents with intermittent exotropia.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
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Abstract
The purpose of this study is to investigate characteristic alterations of functional connectivity (FC) patterns in the primary visual area (V1) in patients with intermittent exotropia (IXT) using resting-state functional magnetic resonance imaging (rs-fMRI) and how they relate to clinical features. Twenty-six IXT patients and 21 age-, sex-, handedness-, and education-matched healthy controls (HCs) underwent rs-fMRI. We performed FC analyses between bilateral V1 and other brain areas and compared FC strength between two groups. A Pearson correlation analysis was used to evaluate the correlation between the FC differences and clinical features. Compared with HCs, patients with IXT showed significantly lower FC of the right V1 with the right calcarine sulcus and right superior occipital gyrus, and the left V1 with right cuneus and right postcentral gyrus. The Newcastle Control Test score was positively correlated with mean FC values between the left inferior parietal lobule and bilateral V1, and between the left supramarginal gyrus and left V1. The duration of IXT was positively correlated with mean FC values between the right inferior occipital gyrus and right V1. Reduced FC between the V1 and various brain regions involved in vision and eye movement processes may be associated with the underlying neural mechanisms of impaired visual function in patients with IXT.
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