Evidence map›Paper›PMID 33841303›Full record

SynthesisFrontiers in neurology2021

Perampanel Improves Cortical Myoclonus and Disability in Progressive Myoclonic Epilepsies: A Case Series and a Systematic Review of the Literature.

Giovanni Assenza, Cristofaro Nocerino, Mario Tombini, Giancarlo Di Gennaro, Alfredo D'Aniello, Alberto Verrotti, Alfonso Marrelli, Lorenzo Ricci, Jacopo Lanzone, Vincenzo Di Lazzaro and 2 more

Registry-linked trialOpen access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06593951 (Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06593951 recruitingnot on this mapstarted 2024, after this paper: background citation

Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1 (EPM1)

Typeobservational_patient_registrySponsorBoston Children's HospitalRan2024 to 2030Enrolled200ConditionsProgressive Myoclonus Epilepsy Type 1, EPM1, CSTB-related Disease, Myoclonus Epilepsies, Progressive
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Review
  9. Article
  10. ILAE Genetics Literacy series: Progressive myoclonus epilepsies.Epileptic disorders : international epilepsy journal with videotape · 2023
    Review
  11. Article
  12. Review
  13. Article
  14. Efficacy and tolerability of antiseizure drugs.Therapeutic advances in neurological disorders · 2021
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Giovanni AssenzaUnit of Neurology, Neurophysiology and Neurobiology, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
Cristofaro NocerinoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, Naples, Italy.
Mario TombiniUnit of Neurology, Neurophysiology and Neurobiology, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
Giancarlo Di GennaroEpilepsy Surgery Center, IRCCS NEUROMED, Pozzilli, Italy.
Alfredo D'AnielloEpilepsy Surgery Center, IRCCS NEUROMED, Pozzilli, Italy.
Alberto VerrottiDepartment of Pediatrics, University of Perugia, Perugia, Italy.
Alfonso MarrelliClinical Neurophysiology Unit -Epilepsy Center, San Salvatore Hospital, L'Aquila, Italy.
Lorenzo RicciUnit of Neurology, Neurophysiology and Neurobiology, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
Jacopo LanzoneUnit of Neurology, Neurophysiology and Neurobiology, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
Vincenzo Di LazzaroUnit of Neurology, Neurophysiology and Neurobiology, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
Leonilda BiloDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, Naples, Italy.
Antonietta CoppolaDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, Naples, Italy.
Università Campus Bio-Medico · ITUniversity of Naples Federico II · ITIstituto Neurologico Mediterraneo · ITSan Salvatore Hospital · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

disabilitymyoclonusperampanelprogressive myoclonic epilepsysystematic (literature) review

Identifiers

PMID33841303
PMCPMC8024635
OpenAlexW3136278741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.