ReviewFrontiers in physiology2021
The Role of Cerebrovascular-Reactivity Mapping in Functional MRI: Calibrated fMRI and Resting-State fMRI.
Review in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Age-Related Low Frequency Amplitude Differences in Resting-State Blood Oxygenation Level-Dependent Signal in the Cerebellum.Human brain mapping · 2026Article
- Neuroradiological features across major psychiatric disorders and behavioral variant of Alzheimer's disease: a concise multimodal synthesis.Psychoradiology · 2026Review
- Voxelwise degree centrality alterations and cognitive performance in severe unilateral M1-segment middle cerebral artery stenosis with ipsilateral watershed infarction.Frontiers in aging neuroscience · 2026Article
- Hypoxia's Impact on Hippocampal Functional Connectivity: Insights from Resting-State fMRI Studies.Brain sciences · 2025Review
- The significance and limited influence of cerebrovascular reactivity on age and sex effects in task- and resting-state brain activity.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- On the merits and potential of advanced neuroimaging techniques in COVID-19: A scoping review.NeuroImage. Clinical · 2024Article
- Multifaceted neural and vascular pathologies after pediatric mild traumatic brain injury.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Acquisition and processing methods of whole-brain layer-fMRI VASO and BOLD: The Kenshu dataset.Aperture neuro · 2023Article
- Hemodynamic timing in resting-state and breathing-task BOLD fMRI.NeuroImage · 2023Article
- Agreement in cerebrovascular reactivity assessed with diffuse correlation spectroscopy across experimental paradigms improves with short separation regression.Neurophotonics · 2023Article
- The many layers of BOLD. The effect of hypercapnic and hyperoxic stimuli on macro- and micro-vascular compartments quantified byJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Understanding recovery of language after stroke: insights from neurovascular MRI studies.Frontiers in language sciences · 2023Article
- Generating dynamic carbon-dioxide traces from respiration-belt recordings: Feasibility using neural networks and application in functional magnetic resonance imaging.Frontiers in neuroimaging · 2023Article
- Toward an integrative neurovascular framework for studying brain networks.Neurophotonics · 2022Article
- Hemodynamic Imaging in Cerebral Diffuse Glioma-Part A: Concept, Differential Diagnosis and Tumor Grading.Cancers · 2022Review
- Lag-Optimized Blood Oxygenation Level Dependent Cerebrovascular Reactivity Estimates Derived From Breathing Task Data Have a Stronger Relationship With Baseline Cerebral Blood Flow.Frontiers in neuroscience · 2022Article
- Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge.NeuroImage · 2021Article
- Metabolism modulates network synchrony in the aging brain.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Effects of Thresholding on Voxel-Wise Correspondence of Breath-Hold and Resting-State Maps of Cerebrovascular Reactivity.Frontiers in neuroscience · 2021Article
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2 authors.
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Abstract
Task and resting-state functional MRI (fMRI) is primarily based on the same blood-oxygenation level-dependent (BOLD) phenomenon that MRI-based cerebrovascular reactivity (CVR) mapping has most commonly relied upon. This technique is finding an ever-increasing role in neuroscience and clinical research as well as treatment planning. The estimation of CVR has unique applications in and associations with fMRI. In particular, CVR estimation is part of a family of techniques called calibrated BOLD fMRI, the purpose of which is to allow the mapping of cerebral oxidative metabolism (CMRO2) using a combination of BOLD and cerebral-blood flow (CBF) measurements. Moreover, CVR has recently been shown to be a major source of vascular bias in computing resting-state functional connectivity, in much the same way that it is used to neutralize the vascular contribution in calibrated fMRI. Furthermore, due to the obvious challenges in estimating CVR using gas challenges, a rapidly growing field of study is the estimation of CVR without any form of challenge, including the use of resting-state fMRI for that purpose. This review addresses all of these aspects in which CVR interacts with fMRI and the role of CVR in calibrated fMRI, provides an overview of the physiological biases and assumptions underlying hypercapnia-based CVR and calibrated fMRI, and provides a view into the future of non-invasive CVR measurement.
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