Evidence map›Paper›PMID 33841188›Full record

ArticleFrontiers in physiology2021

Signal Fingerprinting as a Novel Diagnostic Tool to Identify Conduction Inhomogeneity.

Ziliang Ye, Mathijs S van Schie, Natasja M S de Groot

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Men and women's hearts don't beat the same: Epicardial mapping of Bachmann's bundle.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025
    Article
  2. Sex differences in atrial potential morphology.International journal of cardiology. Heart & vasculature · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Characterization of unipolar electrogram morphology: a novel tool for quantifying conduction inhomogeneity.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  7. Article
  8. Atrial fibrillation.Nature reviews. Disease primers · 2016
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ziliang YeDepartment of Cardiology, Erasmus Medical Center, Rotterdam, Netherlands.
Mathijs S van SchieDepartment of Cardiology, Erasmus Medical Center, Rotterdam, Netherlands.
Natasja M S de GrootDepartment of Cardiology, Erasmus Medical Center, Rotterdam, Netherlands.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInhomogeneous intra-atrial conduction facilitates both initiation and perpetuation of atrial fibrillation (AF) and is reflected in electrogram (EGM) morphology.

objectiveThe primary objective of this study is to investigate regional differences in features of different EGM types during sinus rhythm (SR) and to design a patient-specific signal fingerprint, which quantifies the severity and extensiveness of inhomogeneity in conduction.

methodsPatients (

resultsA total of 1,763,593 EGMs (9,331 ± 3,336 per patient) were classified (Table 1).

conclusionThe signal fingerprint, consisting of quantified EGM features, including the R/S ratio of SPs, the relative frequency distribution of unipolar voltages, the proportion of low-voltage areas, the proportion of the different types of EGMs, and durations of LDP and FDP, may serve as a diagnostic tool to determine the severity and extensiveness of conduction inhomogeneity. Further studies are required to determine whether the signal fingerprint can be used to identify patients at risk for AF onset or progression.

Indexed as

cardiac surgeryconductionelectrogram analysismappingsinus rhythm

Identifiers

PMID33841188
PMCPMC8033016
OpenAlexW3143244323

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.