Evidence map›Paper›PMID 33841073›Full record

ArticleFrontiers in neuroscience2021

Effect of Ketamine on Human Neurochemistry in Posterior Cingulate Cortex: A Pilot Magnetic Resonance Spectroscopy Study at 3 Tesla.

Petr Bednarik, Benjamin Spurny, Leo R Silberbauer, Alena Svatkova, Patricia A Handschuh, Birgit Reiter, Melisande E Konadu, Thomas Stimpfl, Marie Spies, Wolfgang Bogner and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Nature biomedical engineering · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Petr BednarikHigh Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Benjamin SpurnyDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Leo R SilberbauerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Alena SvatkovaDepartment of Medicine III, Clinical Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria.
Patricia A HandschuhDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Birgit ReiterClinical Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Melisande E KonaduDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Thomas StimpflClinical Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Marie SpiesDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Wolfgang BognerHigh Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Rupert LanzenbergerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATKarl Landsteiner Society · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ketamine is a powerful glutamatergic long-lasting antidepressant, efficient in intractable major depression. Whereas ketamine's immediate psychomimetic side-effects were linked to glutamate changes, proton MRS (

Indexed as

depressionglutamateglutamineketamineketamine metabolitesmagnetic resonance spectroscopyneurotransmittersposterior cingulate cortex

Identifiers

PMID33841073
PMCPMC8024494
OpenAlexW3137989757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.