Evidence map›Paper›PMID 33840701›Full record

ArticleInternal medicine (Tokyo, Japan)2021

The Acute Onset of Autoimmune Hepatitis During Pregnancy in the Absence of Hypergammaglobulinemia and Autoantibodies.

Ai Kawada, Shinichi Iwamura, Kenji Yorita, Rikiya Daike, Yu Tanaka, Naoto Kuroda, Yoh Zen, Michiyo Okazaki, Kunihisa Uchita

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ai KawadaDepartment of Internal Medicine, Japanese Red Cross Kochi Hospital, Japan.
Shinichi IwamuraDepartment of Internal Medicine, Japanese Red Cross Kochi Hospital, Japan.
Kenji YoritaDepartment of Diagnostic Pathology, Japanese Red Cross Kochi Hospital, Japan.
Rikiya DaikeDepartment of Internal Medicine, Japanese Red Cross Kochi Hospital, Japan.
Yu TanakaDepartment of Obstetrics and Gynecology, Japanese Red Cross Kochi Hospital, Japan.
Naoto KurodaDepartment of Internal Medicine, Kobe Kyodo Hospital, Japan.
Yoh ZenInstitute of Liver Studies, King's College Hospital and King's College London, UK.
Michiyo OkazakiDepartment of Internal Medicine, Japanese Red Cross Kochi Hospital, Japan.
Kunihisa UchitaDepartment of Internal Medicine, Japanese Red Cross Kochi Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The onset of autoimmune hepatitis (AIH) during pregnancy is rare and often poses a diagnostic challenge. A 29-year-old Japanese woman experienced epigastric pain and nausea during the third trimester of her third pregnancy. Three days after the symptom onset, an emergency Caesarean section was performed because of suspected acute fatty liver of pregnancy; however, the patient's liver dysfunction worsened afterward. Despite normal serum IgG concentration and absence of autoantibodies, biopsy-proven severe hepatitis with centrilobular zonal necrosis and good biochemical response to corticosteroids led to a diagnosis of AIH. Therefore, AIH should be included in the differential diagnosis of liver dysfunction during pregnancy.

Indexed as

Fatty LiverHepatitis, AutoimmuneAdultAutoantibodiesCesarean SectionFemaleHumansHypergammaglobulinemiaPregnancyAutoantibodiesacute hepatitisautoimmune hepatitiscentrilobular zonal necrosispregnancy

Identifiers

PMID33840701
PMCPMC8580773

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.