Evidence map›Paper›PMID 33840692›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Spontaneous Remission of Thrombospondin Type-1 Domain-Containing-Associated Membranous Nephropathy.

Shiika Watanabe, Tomo Suzuki, Wei Han, Mayumi Nakata, Kenichiro Koitabashi, Daisuke Ichikawa, Atsuko Kamijo-Ikemori, Junki Koike, Yugo Shibagaki

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Donor-derived membranous nephropathy.Clinical kidney journal · 2025
    Article
  2. Review
  3. Pathogenesis of autoimmune disease.Nature reviews. Nephrology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shiika WatanabeDivision of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
Tomo SuzukiDivision of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
Wei HanDivision of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
Mayumi NakataDivision of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
Kenichiro KoitabashiDivision of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
Daisuke IchikawaDivision of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
Atsuko Kamijo-IkemoriDepartment of Anatomy, St. Marianna University School of Medicine, Japan.
Junki KoikeDepartment of Diagnostic Pathology, St. Marianna University School of Medicine, Japan.
Yugo ShibagakiDivision of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
St. Marianna University School of Medicine · JPKameda Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membranous nephropathy often achieves spontaneous remission. However, there are scarce reports of spontaneous remission of thrombospondin type-1 domain-containing 7A (THSD7A)-associated membranous nephropathy. A 64-year-old female presented with nephrotic syndrome and edema of the lower extremities. We diagnosed membranous nephropathy by kidney biopsy and confirmed positive THSD7A on immunofluorescence using frozen sections; serum THSD7A antibodies were also detected. Thirty-four months after the initial diagnosis, she achieved a spontaneous complete remission without immunosuppressive therapy. With the complete remission, no serum THSD7A levels were detected. In this study, we describe serial examinations of kidney biopsies and serum THSD7A antibodies.

Indexed as

Glomerulonephritis, MembranousNephrotic SyndromeAutoantibodiesFemaleHumansMiddle AgedReceptors, Phospholipase A2Remission, SpontaneousThrombospondin 1ThrombospondinsAutoantibodiesReceptors, Phospholipase A2Thrombospondin 1Thrombospondinsmembranous nephropathynephrotic syndromespontaneous remissionTHSD7A

Identifiers

PMID33840692
PMCPMC8545627
OpenAlexW3156117662

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.