Evidence map›Paper›PMID 33840415›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2021

[Protective effect of transplantation of human oligodendrocyte precursor cells in a rat model of white matter injury].

Xin Zhong, Zuo Luan, Jing Zang, Qian Guan, Yin-Xiang Yang, Qian Wang, Yuan Shi

Open access · greenAbstract read
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xin ZhongDepartment of Neonatology, Children's Hospital of Chongqing Medical University/National Clinical Research Center for Child Health and Disorders/Ministry of Education Key Laboratory of Child Development and Disorders/Chongqing Engineering Research Center of Stem Cell Therapy, Chongqing 400014, China.
Zuo Luan
Jing Zang
Qian Guan
Yin-Xiang Yang
Qian Wang
Yuan ShiDepartment of Neonatology, Children's Hospital of Chongqing Medical University/National Clinical Research Center for Child Health and Disorders/Ministry of Education Key Laboratory of Child Development and Disorders/Chongqing Engineering Research Center of Stem Cell Therapy, Chongqing 400014, China.
Children's Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the effect of human oligodendrocyte precursor cell (hOPC) transplantation in the treatment of white matter injury (WMI).

methodsNeonatal rats were randomly divided into a sham-operation group, a model group, and a transplantation group (

resultsThe place navigation test using the Morris water maze showed that the model group had a significantly longer escape latency than the sham-operation group, and compared with the model group, the transplantation group had a significant reduction in escape latency (

conclusionsIntrathecal hOPC transplantation may alleviate neurological injury and promote remyelination in a rat model of WMI.

Indexed as

Oligodendrocyte Precursor CellsWhite MatterAnimalsAnimals, NewbornHumansMyelin SheathOligodendrogliaRats

Identifiers

PMID33840415
PMCPMC8050556
OpenAlexW3152850022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.