Evidence map›Paper›PMID 33840257›Full record

ReviewCell transplantation

Surviving the Rookie Virus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2): The Immunopathology of a SARS-CoV2 Infection.

Sheng Feng Tsai, Kang-Yun Lu, Hong-Meng Chuang, Ching-Ann Liu

Open access · goldAbstract readReview
In one paragraph

Review in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Promising Prodiginins Biological Activities.Chemistry & biodiversity · 2025
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Sheng Feng TsaiDepartment of Life Sciences, Agricultural Biotechnology Center, National Chung Hsing University, Taichung.
Kang-Yun LuBioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien.ORCID 0000-0002-0028-5566
Hong-Meng ChuangLaboratory of Translational Medicine Office, Development Center for Biotechnology, Taipei.ORCID 0000-0003-1978-3618
Ching-Ann LiuBioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien.ORCID 0000-0002-0392-7069
China Medical University · TWDevelopment Center for Biotechnology · TWNational Chung Hsing University · TWTzu Chi Foundation · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Until July 29th, the number of confirmed coronavirus (COVID-19) cases worldwide has risen to over 16 million, within which 655 k deaths. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) emerges as the 11th global pandemic disease, showing the highest infectivity and lowest infection fatality rate. In this review, we compare the immunopathology among SARS-CoV, Middle East respiratory syndrome coronavirus, and SARS-CoV2. SARS-CoV2 is similar to SARS-CoV; it can cause lymphocytopenia and a rising granulocyte count. Here we point out the human body and concentrated society make for an excellent incubator for virus evolution. Most research energies put into developing the SARS-CoV2 vaccine are trying to block virus infection. Sixty-five percent of severe patients die with multiple organ failure, inflammation, and cytokine storm, which indicates that the patient's immune system maintains functionality. Finding a way to trigger the specific T cell subset and plasmablast in our body is the best shot to get away with SARS-CoV2.

Indexed as

AnimalsCoronavirusCoronavirus InfectionsCOVID-19Cytokine Release SyndromeHumansInflammationSARS-CoV-2Severe Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirusimmunopathologySARS-CoV2vaccine

Identifiers

PMID33840257
PMCPMC8044562
OpenAlexW3154193666

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.