ArticleArchives of osteoporosis2021
Association between BMI variability and risk of fracture among Korean men and women: a population based study.
Article in Archives of osteoporosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Independent and synergistic associations of cumulative body roundness index and its variability with fragility fracture risk.Lipids in health and disease · 2026Article
- Crosstalk between osteoporosis and fat-infiltrated psoas at the upper lumbar levels.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Severity of Locomotive Syndrome Increases the Risk of Mortality: A Retrospective Study of Patients With Osteoporosis.Cureus · 2025Article
- Risk factors associated with mortality in elderly patients receiving hemiarthroplasty for femoral neck fractures.BMC musculoskeletal disorders · 2025Article
- Weight change patterns across adulthood in relation to osteoporosis and fracture among non-obese individuals.Archives of osteoporosis · 2023Article
- Impact of body mass index on outcomes after lumbar spine surgery.Scientific reports · 2023Article
- Body composition and osteoporotic fracture using anthropometric prediction equations to assess muscle and fat masses.Journal of cachexia, sarcopenia and muscle · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Korean adults aged 50 years and older, the overall risk of fractures increased with greater BMI variability among both men and women, specifically, spinal fractures for men and both spinal and hip fractures for women. PURPOSE: The bone-health-related outcome, such as fractures due to BMI fluctuation, has been understudied within Asian populations. In this large-scale, population-based cohort study in Korea, we aimed to investigate the relationship between variability in body mass index (BMI) and the risk of fractures.
methodsThe study included 166,932 subjects aged ≥ 50 years from the National Health Insurance Service-Health Screening Cohort. The BMI variability value from three follow-up examinations during 2002-2007 was categorized into quartiles. The hazard ratios (HRs) with 95% confidence intervals (CIs) for the effects of BMI variability on the risk of admission from hip, spine, and upper extremity fractures during 2008-2015 were evaluated using a Cox proportional hazards regression analysis.
resultsCompared to those in the lowest BMI variability (1st quartile), men in the highest BMI variability (4th quartile) showed an increased risk of spinal fractures (aHR 1.21, 95% CI 1.07-1.36) with a significant linear trend (P for trend = 0.021). Compared to those in the lowest BMI variability (1st quartile), women in the highest BMI variability (4th quartile) showed an increased risk of hip and spinal fractures (aHR 1.35, 95% CI 1.05-1.69; aHR 1.16, 95% CI 1.05-1.28) with significant linear trends (P for trend = 0.021; P for trend = 0.003, respectively). There was no association between BMI variability and incidents of upper extremity fractures for men or women.
conclusionAssociation between BMI variability and increased fracture risk depended on sex and fracture types. BMI maintenance, instead of high BMI fluctuation, may be beneficial in terms of lowering the overall fracture risk for Korean adults over 50 years old.
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