Evidence map›Paper›PMID 33839918›Full record

Trial reportWorld journal of urology2021

A randomized trial regarding antimicrobial prophylaxis (AMP) in transurethral resection of bladder tumor (TURB).

E Baten, F Van der Aa, H Goethuys, K Slabbert, I Arijs, K van Renterghem

Abstract readMulticenter StudyRandomized Controlled TrialEquivalence Trial
PubMed Publisher
In one paragraph

Trial report in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Essential Japanese Guidelines for the Prevention of Perioperative Infections in the Urological Field: 2023 Edition.International journal of urology : official journal of the Japanese Urological Association · 2025
    Guideline
  2. Selection for antimicrobial prophylaxis in emergency and elective transurethral procedures: Susceptibility pattern in Türkiye.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

E BatenAssociatie Urologie Hageland, Kapellekensweg 10, Kessel-Lo, Belgium. Evert.baten@gmail.com.ORCID http://orcid.org/0000-0002-7487-2907
F Van der AaDepartment of Urology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
H GoethuysZOL Genk, Genk, Belgium.
K SlabbertAssociatie Urologie Hageland, Kapellekensweg 10, Kessel-Lo, Belgium.
I ArijsCenter for Cancer Biology, VIB, 3000, Leuven, Belgium.
K van RenterghemDepartment of Urology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine whether omitting antimicrobial prophylaxis (AMP) in TURB is safe in patients undergoing TURB without an indwelling pre-operative catheter/nephrostomy/DJ and a negative pre-operative urinary culture. MATERIALS AND

methodsA multi-centered randomized controlled trial (RCT) from 17-09-2017 to 31-12-2019 in 5 hospitals. Patients with a pre-operative indwelling catheter/DJ-stent or nephrostomy and a positive pre-operative urinary culture (> 10

results459 Patients were included and 202/459 (44.1%) received AMP vs 257/459 (55.9%) without AMP. Fever occurred in 6/202 [2.9%; 95% CI (1.2-6.6%)] patients with AMP vs 8/257 [3.1%; 95% CI (1.5%-6.1%)] without AMP (p = 0.44). Multivariable, logistic regression showed no significant harm in omitting AMP when controlled for (clot-)retention and tumor size (p = 0.85) and an adjusted risk difference in developing post-TURB fever of 0.0016; 95% CI [- 0.029; 0.032].

conclusionOur data suggest the safety of omitting AMP in patients undergoing TURB without an indwelling, pre-operative catheter/nephrostomy/DJ and a negative pre-operative urinary culture.

Indexed as

AgedAged, 80 and overAmikacinAnti-Bacterial AgentsAntibiotic ProphylaxisCarcinoma, Transitional CellCefazolinCiprofloxacinCystoscopyFemaleFeverHumansLevofloxacinLogistic ModelsMalePostoperative ComplicationsAmikacinAnti-Bacterial AgentsCefazolinCiprofloxacinLevofloxacinAMPAntimicrobial stewardshipFeverMicrobial resistanceRCTTURB

Identifiers

PMID33839918

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.