Evidence map›Paper›PMID 33839893›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

The EANM practice guidelines for parathyroid imaging.

Petra Petranović Ovčariček, Luca Giovanella, Ignasi Carrió Gasset, Elif Hindié, Martin W Huellner, Markus Luster, Arnoldo Piccardo, Theresia Weber, Jean-Noël Talbot, Frederik Anton Verburg

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 3 pooled it
26.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 3 syntheses or guidelines pooled it, 272 citations in OpenAlex.

  1. Guideline
  2. Italian Guidelines for the Management of Sporadic Primary Hyperparathyroidism.Endocrine, metabolic & immune disorders drug targets · 2024
    Guideline
  3. Pooled it
  4. First-line [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  5. Article
  6. Article
  7. The Diagnostic Accuracy of [Diagnostics (Basel, Switzerland) · 2026
    Article
  8. Article
  9. A novel imaging approach in hyperparathyroidism: [68Ga]Ga-Trivehexin PET/CT.European journal of nuclear medicine and molecular imaging · 2026
    Article
  10. Article
  11. Evaluating the preoperative diagnostic value ofJournal of applied clinical medical physics · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Occult Parathyroid Lesions onBiomedicines · 2026
    Article
  17. Article
  18. Review
  19. Challenges and unmet needs of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  20. Article

67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 7 countries.

Petra Petranović OvčaričekEANM Thyroid Committee, Vienna, Austria.
Luca GiovanellaEANM Thyroid Committee, Vienna, Austria.
Ignasi Carrió GassetDepartment of Nuclear Medicine, Hospital Sant Pau and Autonomous University of Barcelona, Barcelona, Spain.
Elif HindiéDepartment of Nuclear Medicine, Bordeaux Hospital and University, Bordeaux, France.
Martin W HuellnerDepartment of Nuclear Medicine, University Hospital and University of Zurich, Zurich, Switzerland.
Markus LusterEANM Thyroid Committee, Vienna, Austria.
Arnoldo PiccardoDepartment of Nuclear Medicine, E.O. Ospedali Galliera, Genoa, Italy.
Theresia WeberDepartment of Endocrine Surgery, Katholisches Klinikum Mainz, Mainz, Germany.
Jean-Noël TalbotNuclear Medicine, Hospital Tenon APHP and Sorbonne University, Paris, France.
Frederik Anton VerburgEANM Thyroid Committee, Vienna, Austria. f.verburg@erasmusmc.nl.
Ente Ospedaliero Ospedali Galliera · ITErasmus MC · NLEuropean Association of Nuclear Medicine · ATHôpital Tenon · FRPhilipps University of Marburg · DEUniversitat Autònoma de Barcelona · ESUniversité de Bordeaux · FRUniversity Hospital of Zurich · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNuclear medicine parathyroid imaging is important in the identification of hyperfunctioning parathyroid glands in primary hyperparathyroidism (pHPT), but it may be also valuable before surgical treatment in secondary hyperparathyroidism (sHPT). Parathyroid radionuclide imaging with scintigraphy or positron emission tomography (PET) is a highly sensitive procedure for the assessment of the presence and number of hyperfunctioning parathyroid glands, located either at typical sites or ectopically. The treatment of pHPT is mostly directed toward minimally invasive parathyroidectomy, especially in cases with a single adenoma. In experienced hands, successful surgery depends mainly on the exact preoperative localization of one or more hyperfunctioning parathyroid adenomas. Failure to preoperatively identify the hyperfunctioning parathyroid gland challenges minimally invasive parathyroidectomy and might require bilateral open neck exploration.

methodsOver a decade has now passed since the European Association of Nuclear Medicine (EANM) issued the first edition of the guideline on parathyroid imaging, and a number of new insights and techniques have been developed since. The aim of the present document is to provide state-of-the-art guidelines for nuclear medicine physicians performing parathyroid scintigraphy, single-photon emission computed tomography/computed tomography (SPECT/CT), positron emission tomography/computed tomography (PET/CT), and positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with pHPT, as well as in those with sHPT.

conclusionThese guidelines are written and authorized by the EANM to promote optimal parathyroid imaging. They will assist nuclear medicine physicians in the detection and correct localization of hyperfunctioning parathyroid lesions.

Indexed as

Hyperparathyroidism, PrimaryNuclear MedicineHumansParathyroid GlandsPositron Emission Tomography Computed TomographyRadionuclide ImagingSensitivity and SpecificityTechnetium Tc 99m SestamibiTechnetium Tc 99m Sestamibi[11C]CH[11C]MET18F-labeled choline analogues4D-CT[99mTc]Tc-MIBI[99mTc]Tc-tetrofosminCervical ultrasonographyDual-phase scintigraphyDual-tracer scintigraphyHyperparathyroidismMRIParathyroid scintigraphyPET/CTSPECT/CT

Identifiers

PMID33839893
PMCPMC8263421
OpenAlexW3155440028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.