Evidence map›Paper›PMID 33839884›Full record

ReviewCurrent genetics2021

Novel self-regulation strategy of a small heat shock protein for prodigious and rapid expression on demand.

Tsukumi Miwa, Hideki Taguchi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Tsukumi MiwaCell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, S2-19, Nagatsuta 4259, Midori-ku, Yokohama, 226-8503, Japan.
Hideki TaguchiCell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, S2-19, Nagatsuta 4259, Midori-ku, Yokohama, 226-8503, Japan. taguchi@bio.titech.ac.jp.ORCID http://orcid.org/0000-0002-6612-9339
Tokyo Institute of Technology · JP

Funding

Ministry of Education, Culture, Sports, Science and Technology 26116002
6 · The paper itself

Abstract

In this mini-review, we summarize the known and novel regulation mechanisms of small heat shock proteins (sHsps). sHsps belong to a well-conserved family of ATP-independent oligomeric chaperones that protect denatured proteins from forming irreversible aggregates by co-aggregation. The functions of sHsps as a first line of defense against acute stresses require the high abundance of sHsps on demand. The heat stress-induced expression of IbpA, one of the sHsps in Escherichia coli, is regulated by σ

Indexed as

Gene Expression Regulation, BacterialEscherichia coliEscherichia coli ProteinsHeat-Shock ProteinsHeat-Shock Proteins, SmallSigma FactorEscherichia coli ProteinsHeat-Shock ProteinsHeat-Shock Proteins, Smallheat-shock sigma factor 32IbpA protein, E coliSigma FactorIbpAIbpBMRNA bindingProtein aggregatesSelf-regulationSHspsSmall heat shock proteinsTranslation regulation

Identifiers

PMID33839884
OpenAlexW3153171823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.