Evidence map›Paper›PMID 33839876›Full record

ArticleActa neurochirurgica. Supplement2021

Safety and Feasibility of Lumbar Cerebrospinal Fluid Pressure and Intraspinal Pressure Studies in Cervical Stenosis: A Case Series.

Carl Moritz Zipser, José Miguel Spirig, José Aguirre, Anna-Sophie Hofer, Nikolai Pfender, Markus Hupp, Armin Curt, Mazda Farshad, Martin Schubert

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Acta neurochirurgica. Supplement, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
9.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Carl Moritz ZipserDepartment of Neurology and Neurophysiology, Balgrist University Hospital, Zurich, Switzerland. carlmoritz.zipser@balgrist.ch.
José Miguel SpirigBalgrist University Hospital, University Spine Center, Zurich, Switzerland.
José AguirreDepartment of Anesthesiology, Balgrist University Hospital, Zurich, Switzerland.
Anna-Sophie HoferDepartment of Neurosurgery, University Hospital Zurich, Zurich, Switzerland.
Nikolai PfenderDepartment of Neurology and Neurophysiology, Balgrist University Hospital, Zurich, Switzerland.
Markus HuppDepartment of Neurology and Neurophysiology, Balgrist University Hospital, Zurich, Switzerland.
Armin CurtDepartment of Neurology and Neurophysiology, Balgrist University Hospital, Zurich, Switzerland.
Mazda FarshadBalgrist University Hospital, University Spine Center, Zurich, Switzerland.
Martin SchubertDepartment of Neurology and Neurophysiology, Balgrist University Hospital, Zurich, Switzerland.
Universitätsklinik Balgrist · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDegenerative cervical myelopathy (DCM) leads to functional impairment by compression of the spinal cord and nerve roots. In DCM, the dynamics of cerebrospinal fluid pressure (CSFP) and intraspinal pressure (ISP), as well as spinal cord perfusion pressure (SCPP) remain not investigated yet. Recent technical advances have enabled investigation of these parameters in acute spinal cord injury (SCI). We aim to investigate the properties of CSFP/ISP and spinal cord hemodynamics during and after decompressive surgery in DCM. MATERIALS AND

methodsFour patients with DCM were enrolled; during surgery and 24 h postoperative, ISP at level was measured in one patient, and CSFP was measured in two patients. In one patient, CSFP was recorded at bedside before surgery.

resultsAll measurements were conducted without adverse events and were well tolerated. With CSFP analysis, post-decompression Queckenstedt's test was responsive in two patients (i.e., jugular vein compression resulted in an elevation of CSFP pressure). In the patient whose CSFP was tested at bedside, Queckenstedt's test was not responsive before decompression. Individual optimum SCPPs were calculated to be between 70 and 75 mmHg.

conclusionISP and CSFP can reflect spinal compression and sufficient decompression. A better understanding and systematic monitoring possibly lead to improved hemodynamic management and may allow early recognition of postoperative complications such as swelling and bleeding.

Indexed as

Cerebrospinal Fluid PressureConstriction, PathologicFeasibility StudiesHumansSpinal Cord InjuriesCerebrospinal fluid pressureDegenerative cervical myelopathyIntraspinal pressureNeurophysiologySpinal cord injurySpinal cord perfusionSpinal stenosis

Identifiers

PMID33839876
OpenAlexW3153257396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.