Evidence map›Paper›PMID 33839786›Full record

ArticleJournal of the National Cancer Institute2021

Medical Financial Hardship in Survivors of Adolescent and Young Adult Cancer in the United States.

Amy D Lu, Zhiyuan Zheng, Xuesong Han, Ruowen Qi, Jingxuan Zhao, K Robin Yabroff, Paul C Nathan

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
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  11. Journal of adolescent and young adult oncology · 2025
    Article
  12. Article
  13. Association of cancer with racial disparities in financial health: a national cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Observational
  14. Enduring Economic Effects of a Cancer Diagnosis in Adolescence and Young Adulthood.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Article
  15. Quantifying and addressing self-defined needs in cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Amy D LuDepartment of Paediatrics, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-3095-7036
Zhiyuan ZhengSurveillance and Health Services Research, American Cancer Society, Atlanta, GA, USA.
Xuesong HanSurveillance and Health Services Research, American Cancer Society, Atlanta, GA, USA.ORCID 0000-0001-7159-7949
Ruowen QiRollins School of Public Health, Emory University, Atlanta, GA, USA.
Jingxuan ZhaoSurveillance and Health Services Research, American Cancer Society, Atlanta, GA, USA.ORCID 0000-0002-2733-2000
K Robin YabroffSurveillance and Health Services Research, American Cancer Society, Atlanta, GA, USA.ORCID 0000-0003-0644-5572
Paul C NathanDepartment of Paediatrics, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-0334-0871
American Cancer Society · USUniversity of Toronto · CAEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer and its treatment can result in lifelong medical financial hardship, which we aimed to describe among adult survivors of adolescent and young adult (AYA) cancers in the United States.

methodsWe identified adult (aged ≥18 years) survivors of AYA cancers (diagnosed ages 15-39 years) and adults without a cancer history from the 2010-2018 National Health Interview Surveys. Proportions of respondents reporting measures in different hardship domains (material [eg, problems paying bills], psychological [eg, distress], and behavioral [eg, forgoing care due to cost]) were compared between groups using multivariable logistic regression models and hardship intensity (cooccurrence of hardship domains) using ordinal logistic regression. Cost-related changes in prescription medication use were assessed separately.

resultsA total of 2588 AYA cancer survivors (median = 31 [interquartile range = 26-35] years at diagnosis; 75.0% more than 6 years and 50.0% more than 16 years since diagnosis) and 256 964 adults without a cancer history were identified. Survivors were more likely to report at least 1 hardship measure in material (36.7% vs 27.7%, P < .001) and behavioral (28.4% vs 21.2%, P < .001) domains, hardship in all 3 domains (13.1% vs 8.7%, P < .001), and at least 1 cost-related prescription medication nonadherence (13.7% vs 10.3%, P = .001) behavior.

conclusionsAdult survivors of AYA cancers are more likely to experience medical financial hardship across multiple domains compared with adults without a cancer history. Health-care providers must recognize this inequity and its impact on survivors' health, and multifaceted interventions are necessary to address underlying causes.

Indexed as

Cancer SurvivorsNeoplasmsAdolescentAdultFinancial StressHealth ExpendituresHumansSurvivorsUnited StatesYoung Adult

Identifiers

PMID33839786
PMCPMC8328985
OpenAlexW3153492845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.