Evidence map›Paper›PMID 33839749›Full record

SynthesisBJS open2021

Identifying predictors of ventral hernia recurrence: systematic review and meta-analysis.

S G Parker, S Mallett, L Quinn, C P J Wood, R W Boulton, S Jamshaid, M Erotocritou, S Gowda, W Collier, A A O Plumb and 3 more

Erratum issued Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BJS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06864377 (Ventral Hernia Improvement of Treatment and Life), which is not on this map. Cited by 73 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06864377 enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Ventral Hernia Improvement of Treatment and Life

Typeobservational_patient_registrySponsorLine MarkerRan2025 to 2027Enrolled300ConditionsIncisional Hernia, Parastomal Hernia, Ventral HerniaArmsQuality of life questionnair
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  18. Potential and feasibility of preoptimisation in ventral hernia repair- a focus group study.Hernia : the journal of hernias and abdominal wall surgery · 2026
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

S G ParkerAbdominal Wall Unit, Department of Surgery, University College Hospital, London, UK.
S MallettInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
L QuinnInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
C P J WoodAbdominal Wall Unit, Department of Surgery, University College Hospital, London, UK.
R W BoultonAbdominal Wall Unit, Department of Surgery, University College Hospital, London, UK.
S JamshaidAbdominal Wall Unit, Department of Surgery, University College Hospital, London, UK.
M ErotocritouAbdominal Wall Unit, Department of Surgery, University College Hospital, London, UK.
S GowdaAbdominal Wall Unit, Department of Surgery, University College Hospital, London, UK.
W CollierAbdominal Wall Unit, Department of Surgery, University College Hospital, London, UK.
A A O PlumbCentre of Medical Imaging, University College Hospital, London, UK.
A C J WindsorAbdominal Wall Unit, Department of Surgery, University College Hospital, London, UK.
L ArcherCentre for Prognosis Research, School of Primary, Community and Social Care, Keele University, Keele, UK.
S HalliganCentre of Medical Imaging, University College Hospital, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVentra hernias are increasing in prevalence and many recur despite attempted repair. To date, much of the literature is underpowered and divergent. As a result there is limited high quality evidence to inform surgeons succinctly which perioperative variables influence postoperative recurrence. This systematic review aimed to identify predictors of ventral hernia recurrence.

methodsPubMed was searched for studies reporting prognostic data of ventral hernia recurrence between 1 January 1995 and 1 January 2018. Extracted data described hernia type (primary/incisional), definitions of recurrence, methods used to detect recurrence, duration of follow-up, and co-morbidity. Data were extracted for all potential predictors, estimates and thresholds described. Random-effects meta-analysis was used. Bias was assessed with a modified PROBAST (Prediction model Risk Of Bias ASsessment Tool).

resultsScreening of 18 214 abstracts yielded 274 individual studies for inclusion. Hernia recurrence was defined in 66 studies (24.1 per cent), using 41 different unstandardized definitions. Three patient variables (female sex, age 65 years or less, and BMI greater than 25, 30, 35 or 40 kg/m2), five patient co-morbidities (smoking, diabetes, chronic obstructive pulmonary disease, ASA grade III-IV, steroid use), two hernia-related variables (incisional/primary, recurrent/primary), six intraoperative variables (biological mesh, bridged repair, open versus laparoscopic surgery, suture versus mesh repair, onlay/retrorectus, intraperitoneal/retrorectus), and six postoperative variables (any complication, surgical-site occurrence, wound infection, seroma, haematoma, wound dehiscence) were identified as significant prognostic factors for hernia recurrence.

conclusionThis study summarized the current evidence base for predicting ventral hernia recurrence. Results should inform best practice and future research.

Indexed as

LaparoscopySurgical MeshSuture TechniquesHernia, VentralHerniorrhaphyHumansRandomized Controlled Trials as TopicRecurrenceTreatment Outcome

Identifiers

PMID33839749
PMCPMC8038271

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.