Evidence map›Paper›PMID 33838685›Full record

SynthesisEnvironmental health : a global access science source2021

Acute and chronic exposure to air pollution in relation with incidence, prevalence, severity and mortality of COVID-19: a rapid systematic review.

Patrick D M C Katoto, Amanda S Brand, Buket Bakan, Paul Musa Obadia, Carsi Kuhangana, Tony Kayembe-Kitenge, Joseph Pyana Kitenge, Celestin Banza Lubaba Nkulu, Jeroen Vanoirbeek, Tim S Nawrot and 2 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Ambient Air Pollution and COVID-19 in California.Research report (Health Effects Institute) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Household air pollution and risk of pulmonary tuberculosis in HIV-Infected adults.Environmental health : a global access science source · 2024
    Article
  18. Indirect Effects of PMAnnals of global health · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 5 countries.

Patrick D M C KatotoDepartment of Medicine and Centre for Infectious Diseases, Faculty of Medicine and Health Sciences, Stellenbosch University, Francie van Zijl Drive, Tygerberg, Cape Town, 7505, South Africa. katoto@sun.ac.za.ORCID 0000-0002-0553-201X
Amanda S BrandCentre for Evidence-Based Health Care, Division of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University, Cape Town, South Africa.
Buket BakanDepartment of Molecular Biology and Genetics, Faculty of Science, Ataturk University, 25240, Erzurum, Turkey.
Paul Musa ObadiaCentre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Herestraat 49 (O&N 706), B-3000, Leuven, Belgium.
Carsi KuhanganaUnit of Toxicology and Environment, School of Public Health, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo.
Tony Kayembe-KitengeCentre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Herestraat 49 (O&N 706), B-3000, Leuven, Belgium.
Joseph Pyana KitengeOccupational Medicine and Environmental Health, Department of Public Health, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo.
Celestin Banza Lubaba NkuluUnit of Toxicology and Environment, School of Public Health, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo.
Jeroen VanoirbeekCentre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Herestraat 49 (O&N 706), B-3000, Leuven, Belgium.
Tim S NawrotCentre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Herestraat 49 (O&N 706), B-3000, Leuven, Belgium.
Peter HoetCentre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Herestraat 49 (O&N 706), B-3000, Leuven, Belgium.
Benoit NemeryCentre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Herestraat 49 (O&N 706), B-3000, Leuven, Belgium. ben.nemery@kuleuven.be.
University of Lubumbashi · CDKU Leuven · BEStellenbosch University · ZAAtatürk University · TRDepartment of Public Health · USHasselt University · BE

Funding

University of Pittsburgh HIV-Comorbidities Research Training Program in South AfricaD43TW010937 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NACHEGA, JEAN BISIMWA, SEEDAT, SORAYA · 2019 to 2023
$1.2M
FIC NIH HHS D43 TW010937
6 · The paper itself

Abstract

backgroundAir pollution is one of the world's leading mortality risk factors contributing to seven million deaths annually. COVID-19 pandemic has claimed about one million deaths in less than a year. However, it is unclear whether exposure to acute and chronic air pollution influences the COVID-19 epidemiologic curve.

methodsWe searched for relevant studies listed in six electronic databases between December 2019 and September 2020. We applied no language or publication status limits. Studies presented as original articles, studies that assessed risk, incidence, prevalence, or lethality of COVID-19 in relation with exposure to either short-term or long-term exposure to ambient air pollution were included. All patients regardless of age, sex and location diagnosed as having COVID-19 of any severity were taken into consideration. We synthesised results using harvest plots based on effect direction.

resultsIncluded studies were cross-sectional (n = 10), retrospective cohorts (n = 9), ecological (n = 6 of which two were time-series) and hypothesis (n = 1). Of these studies, 52 and 48% assessed the effect of short-term and long-term pollutant exposure, respectively and one evaluated both. Pollutants mostly studied were PM

conclusionThe body of evidence indicates that both acute and chronic exposure to air pollution can affect COVID-19 epidemiology. The evidence is unclear for acute exposure due to a higher level of bias in existing studies as compared to moderate evidence with chronic exposure. Public health interventions that help minimize anthropogenic pollutant source and socio-economic injustice/disparities may reduce the planetary threat posed by both COVID-19 and air pollution pandemics.

Indexed as

Air PollutantsAir PollutionCOVID-19Environmental ExposureHumansIncidenceNitrogen DioxideOzoneParticulate MatterPrevalencePrognosisSulfur DioxideAir PollutantsNitrogen DioxideOzoneParticulate MatterSulfur DioxideBurdenLethalityLong-term air pollutionSARS-CoV-2Short-termSusceptibility

Identifiers

PMID33838685
PMCPMC8035877
OpenAlexW3155805203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.