Evidence map›Paper›PMID 33838445›Full record

ArticleJournal of the mechanical behavior of biomedical materials2021

Axially- and torsionally-polarized radially converging shear wave MRE in an anisotropic phantom made via Embedded Direct Ink Writing.

Martina Guidetti, Marco Andrea Zampini, Yizhou Jiang, Chiara Gambacorta, Joshua P Smejkal, Joseph Crutison, Yayue Pan, Dieter Klatt, Thomas J Royston

Open access · greenAbstract read
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Martina GuidettiUniversity of Illinois at Chicago, Richard and Loan Hill Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA. Electronic address: mguide2@uic.edu.
Marco Andrea ZampiniMR Solutions Ltd, Ashbourne House, Old Portsmouth Rd, Guildford, United Kingdom.
Yizhou JiangUniversity of Illinois at Chicago, Department of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Chiara GambacortaUniversity of Illinois at Chicago, Richard and Loan Hill Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Joshua P SmejkalUniversity of Illinois at Chicago, Richard and Loan Hill Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Joseph CrutisonUniversity of Illinois at Chicago, Richard and Loan Hill Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Yayue PanUniversity of Illinois at Chicago, Department of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Dieter KlattUniversity of Illinois at Chicago, Richard and Loan Hill Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Thomas J RoystonUniversity of Illinois at Chicago, Richard and Loan Hill Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
University of Illinois Chicago · USMaterials Solutions (United Kingdom) · GB

Funding

Noninvasive Tools for Assessing Muscle Structure and FunctionR01AR071162 · NIAMS · NORTHWESTERN UNIVERSITY · PI ERIC JON PERREAULT · 2016 to 2026
$6.1M
NIAMS NIH HHS R01 AR071162
6 · The paper itself

Abstract

Magnetic Resonance Elastography (MRE) is a non-invasive imaging method to quantitatively map the shear viscoelastic properties of soft tissues. In this study, Embedded Direct Ink Writing is used to fabricate a muscle mimicking anisotropic phantom that may serve as a standard for imaging studies of anisotropic materials. The technique allowed us to obtain a long shelf life silicone-based phantom expressing transverse isotropic mechanical properties. Another goal of the present investigation is to introduce a torsionally-polarized, radially-converging shear wave actuation method for MRE. The implemented design for this novel setup was first validated via its application to isotropic and homogeneous gelatin phantoms. Then, a comparison of the resulting complex wave images from axially- and torsionally-polarized MRE on the developed anisotropic phantom and on a skeletal muscle murine sample is presented, highlighting the value of using multiple actuation and motion encoding polarization directions when studying anisotropic materials.

Indexed as

Elasticity Imaging TechniquesAnimalsElasticityInkMagnetic Resonance ImagingMicePhantoms, ImagingWritingAdditive manufacturingComplex shear moduliEmbedded Direct Ink WritingMagnetic Resonance ElastographyPhantom designTabletop MRI

Identifiers

PMID33838445
PMCPMC8137604
OpenAlexW3144765540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.