Evidence map›Paper›PMID 33838146›Full record

ArticleNeuropsychologia2021

Fornix white matter microstructure differentially predicts false recollection rates in older and younger adults.

Jordan D Chamberlain, Indira C Turney, Jordan T Goodman, Jonathan G Hakun, Nancy A Dennis

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropsychologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Relationships between Inflammation and Age-Related Neurocognitive Changes.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jordan D ChamberlainDepartment of Psychology, The Pennsylvania State University, University Park, PA, USA.
Indira C TurneyDepartment of Psychology, The Pennsylvania State University, University Park, PA, USA; Department of Neurology, University of Columbia Medical Center, New York, NY, USA.
Jordan T GoodmanDepartment of Psychology, The Pennsylvania State University, University Park, PA, USA.
Jonathan G HakunDepartment of Psychology, The Pennsylvania State University, University Park, PA, USA; Department of Neurology, The Pennsylvania State University Hershey Medical Center, Hershey, PA, USA.
Nancy A DennisDepartment of Psychology, The Pennsylvania State University, University Park, PA, USA. Electronic address: nad12@psu.edu.
Pennsylvania State University · US

Funding

Self-regulation of Health Promotion: the Roles of Momentary Variability in Working Memory Capacity and Neurocognitive AgingR00AG056670 · NIA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI HAKUN, JONATHAN G. · 2019 to 2021
$721k
Self-regulation of Health Promotion: the Roles of Momentary Variability in Working Memory Capacity and Neurocognitive AgingK99AG056670 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI HAKUN, JONATHAN G. · 2017 to 2018
$201k
NIA NIH HHS K99 AG056670NIA NIH HHS R00 AG056670
6 · The paper itself

Abstract

Healthy aging is accompanied by increased false remembering in addition to reduced successful remembering in older adults. Neuroimaging studies implicate age-related differences in the involvement of medial temporal lobe and fronto-parietal regions in mediating highly confident false recollection. However, no studies have directly examined the relationship between white matter microstructure and false recollection in younger and older adults. Using diffusion-weighted imaging and probabilistic tractography, we examined how white matter microstructure within tracts connecting the hippocampus and the fronto-parietal retrieval network contribute to false recollection rates in healthy younger and older adults. We found only white matter microstructure within the fornix contributed to false recollection rates, and this relationship was specific to older adults. Fornix white matter microstructure did not contribute to true recollection rate, nor did common white matter contribute to false recollection, suggesting fornix microstructure is explicitly associated with highly confident false memories in our sample of older adults. These findings underlie the importance of examining microstructural correlates associated with false recollection in younger and older adults.

Indexed as

White MatterAgedHippocampusHumansMemoryMental RecallTemporal LobeDiffusion weighted imagingFalse memoryOlder adults

Identifiers

PMID33838146
PMCPMC8674925
OpenAlexW3140100588

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.