Evidence map›Paper›PMID 33837868›Full record

ReviewNeurochemical research2021

Sensing and Regulating Synaptic Activity by Astrocytes at Tripartite Synapse.

José Antonio Noriega-Prieto, Alfonso Araque

Abstract readReview
In one paragraph

Review in Neurochemical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Connecting the Dots: AMOG/βInternational journal of molecular sciences · 2025
    Review
  9. Article
  10. Article
  11. Astrocytes integrate time and space.Neural regeneration research · 2025
    Article
  12. Astrocytes and Tinnitus.Brain sciences · 2024
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

José Antonio Noriega-PrietoDepartment of Neuroscience, University of Minnesota, Minneapolis, MN, 55455, USA.
Alfonso AraqueDepartment of Neuroscience, University of Minnesota, Minneapolis, MN, 55455, USA. araque@umn.edu.ORCID http://orcid.org/0000-0003-3840-1144

Funding

Astrocyte activity in amygdala-related fear conditioned behaviorsR01MH119355 · NIMH · UNIVERSITY OF MINNESOTA · PI ARAQUE, ALFONSO, KOFUJI, PAULO · 2020 to 2024
$2.3M
Role of astrocytes in dopamine signaling and psychostimulant effectsR01DA048822 · NIDA · UNIVERSITY OF MINNESOTA · PI ARAQUE, ALFONSO · 2019 to 2023
$1.8M
Astrocyte-neuron interaction in behavior driven by striatal information processingR01NS097312 · NINDS · UNIVERSITY OF MINNESOTA · PI ARAQUE, ALFONSO, REDISH, A DAVID · 2016 to 2019
$1.8M
NIDA NIH HHS R01 DA048822NIDA NIH HHS R01DA048822NIMH NIH HHS R01 MH119355NINDS NIH HHS R01 NS097312NINDS NIH HHS R01NS097312
6 · The paper itself

Abstract

Astrocytes are recognized as more important cells than historically thought in synaptic function through the reciprocal exchange of signaling with the neuronal synaptic elements. The idea that astrocytes are active elements in synaptic physiology is conceptualized in the Tripartite Synapse concept. This review article presents and discusses recent representative examples that highlight the heterogeneity of signaling in tripartite synapse function and its consequences on neural network function and animal behavior.

Indexed as

AnimalsAstrocytesBehavior, AnimalNeuronal PlasticityNeurotransmitter AgentsSynapsesSynaptic TransmissionNeurotransmitter AgentsAstrocytesGliotransmissionNetwork functionSynaptic functionTripartite synapse

Identifiers

PMID33837868
PMCPMC10159683

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.