Evidence map›Paper›PMID 33837856›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2021

Ruthenium (II)/allopurinol complex inhibits breast cancer progression via multiple targets.

Ingrid O Travassos, Francyelli Mello-Andrade, Raíssa P Caldeira, Wanessa C Pires, Paula F F da Silva, Rodrigo S Correa, Tamara Teixeira, Alisson Martins-Oliveira, Alzir A Batista, Elisângela P de Silveira-Lacerda

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Ingrid O TravassosLaboratório de Genética Molecular E Citogenética Humana, sala 213, Departamento de Genética, Instituto de Ciências Biológicas I, Campus Samambaia, Universidade Federal de Goiás, Avenida Esperança, s/n, Cx Postal: 131, Goiânia, Goiás, CEP 74690-900, Brazil.ORCID 0000-0002-7868-6933
Francyelli Mello-AndradeLaboratório de Genética Molecular E Citogenética Humana, sala 213, Departamento de Genética, Instituto de Ciências Biológicas I, Campus Samambaia, Universidade Federal de Goiás, Avenida Esperança, s/n, Cx Postal: 131, Goiânia, Goiás, CEP 74690-900, Brazil.ORCID 0000-0001-7389-6125
Raíssa P CaldeiraLaboratório de Genética Molecular E Citogenética Humana, sala 213, Departamento de Genética, Instituto de Ciências Biológicas I, Campus Samambaia, Universidade Federal de Goiás, Avenida Esperança, s/n, Cx Postal: 131, Goiânia, Goiás, CEP 74690-900, Brazil.
Wanessa C PiresLaboratório de Genética Molecular E Citogenética Humana, sala 213, Departamento de Genética, Instituto de Ciências Biológicas I, Campus Samambaia, Universidade Federal de Goiás, Avenida Esperança, s/n, Cx Postal: 131, Goiânia, Goiás, CEP 74690-900, Brazil.
Paula F F da SilvaLaboratório de Genética Molecular E Citogenética Humana, sala 213, Departamento de Genética, Instituto de Ciências Biológicas I, Campus Samambaia, Universidade Federal de Goiás, Avenida Esperança, s/n, Cx Postal: 131, Goiânia, Goiás, CEP 74690-900, Brazil.
Rodrigo S CorreaDepartment of Chemistry, Federal University of Ouro Preto-UFOP, Ouro Preto, MG, 35400-000, Brazil.ORCID 0000-0003-2783-0816
Tamara TeixeiraDepartment of Chemistry, Federal University of Ouro Preto-UFOP, Ouro Preto, MG, 35400-000, Brazil.
Alisson Martins-OliveiraUniEvangelica University Center, Anapolis, GO, 75083-515, Brazil.
Alzir A BatistaDepartment of Chemistry, Federal University of Sao Carlos-UFSCar, Sao Carlos, SP, 13565-905, Brazil.
Elisângela P de Silveira-LacerdaLaboratório de Genética Molecular E Citogenética Humana, sala 213, Departamento de Genética, Instituto de Ciências Biológicas I, Campus Samambaia, Universidade Federal de Goiás, Avenida Esperança, s/n, Cx Postal: 131, Goiânia, Goiás, CEP 74690-900, Brazil. silveiralacerda@gmail.com.ORCID 0000-0002-4143-9007
Universidade Federal de Goiás · BRUniversidade Federal de Ouro Preto · BRInstituto Federal de Goiás · BRUniversidade Evangelica de Goiás · BRUniversidade Federal de São Carlos · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal complexes based on ruthenium have established excellent activity with less toxicity and great selectivity for tumor cells. This study aims to assess the anticancer potential of ruthenium(II)/allopurinol complexes called [RuCl

Indexed as

AllopurinolAnimalsAntineoplastic AgentsAscitic FluidCell CycleCell Migration AssaysCells, CulturedCell SurvivalFemaleFibroblastsHumansMammary Neoplasms, AnimalMiceNeoplasms, ExperimentalRuthenium CompoundsAllopurinolAntineoplastic Agentsruthenium chlorideRuthenium CompoundsCell deathDNA damageROSTriple-negative breast cancer

Identifiers

PMID33837856
OpenAlexW3146234032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.